Evidence map›Paper›PMID 37766240›Full record

ArticleViruses2023

Inactivation of Bacteriophage ɸ6 and SARS-CoV-2 in Antimicrobial Surface Tests.

Sabine Poelzl, Julia Rieger, Kurt Zatloukal, Stefan Augl, Maximilian Stummer, Andreas Hinterer, Clemens Kittinger

Abstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sabine PoelzlDiagnostic and Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Neue Stiftingtalstraße 2A, 8010 Graz, Austria.ORCID 0000-0001-6838-1047
Julia RiegerDiagnostic and Research Institute of Pathology, Medical University Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.
Kurt ZatloukalDiagnostic and Research Institute of Pathology, Medical University Graz, Neue Stiftingtalstraße 6, 8010 Graz, Austria.ORCID 0000-0001-5299-7218
Stefan AuglDepartment of Materials Technology, University of Applied Sciences Upper Austria, Stelzhamerstraße 23, 4600 Wels, Austria.
Maximilian StummerINOCON Technologie GmbH, Wiener Straße 3, 4800 Attnang-Puchheim, Austria.
Andreas HintererINOCON Technologie GmbH, Wiener Straße 3, 4800 Attnang-Puchheim, Austria.
Clemens KittingerDiagnostic and Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Neue Stiftingtalstraße 2A, 8010 Graz, Austria.ORCID 0000-0001-8472-2155

Funding

Austrian Research Promotion Agency 881059
6 · The paper itself

Abstract

Due to the COVID-19 pandemic, researchers have focused on new preventive measures to limit the spread of SARS-CoV-2. One promising application is the usage of antimicrobial materials on often-touched surfaces to reduce the load of infectious virus particles. Since tests with in vitro-propagated SARS-CoV-2 require biosafety level 3 (BSL-3) laboratories with limited capacities and high costs, experiments with an appropriate surrogate like the bacteriophage ɸ6 are preferred in most studies. The aim of this study was to compare ɸ6 and SARS-CoV-2 within antiviral surface tests. Different concentrations of copper coatings on polyethylene terephthalate (PET) were used to determine their neutralizing activity against ɸ6 and SARS-CoV-2. The incubation on the different specimens led to similar inactivation of both SARS-CoV-2 and ɸ6. After 24 h, no infectious virus particles were evident on any of the tested samples. Shorter incubation periods on specimens with high copper concentrations also showed a complete inactivation. In contrast, the uncoated PET foils resulted only in a negligible reduced inactivation during the one-hour incubation. The similar reduction rate for ɸ6 and SARS-CoV-2 in our experiments provide further evidence that the bacteriophage ɸ6 is an adequate model organism for SARS-CoV-2 for this type of testing.

Indexed as

Bacteriophage phi 6SARS-CoV-2Virus InactivationCopperCOVID-19HumansPolyethylene TerephthalatesCopperPolyethylene Terephthalatesantimicrobial surfacebacteriophageɸ6SARS-CoV-2

Identifiers

PMID37766240
PMCPMC10535131

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.