Evidence map›Paper›PMID 37766140›Full record

ArticleVaccines2023

Long-Term Immune Response Profiles to SARS-CoV-2 Vaccination and Infection in People with Multiple Sclerosis on Anti-CD20 Therapy.

Christina Woopen, Marie Dunsche, Georges Katoul Al Rahbani, Anja Dillenseger, Yassin Atta, Rocco Haase, Catarina Raposo, Rosetta Pedotti, Tjalf Ziemssen, Katja Akgün

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Christina WoopenCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.ORCID 0000-0002-7896-8682
Marie DunscheCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.
Georges Katoul Al RahbaniCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.ORCID 0000-0002-2969-0717
Anja DillensegerCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.
Yassin AttaCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.
Rocco HaaseCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.ORCID 0000-0003-2465-4909
Catarina RaposoF. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.ORCID 0000-0002-1466-1542
Rosetta PedottiF. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland.
Tjalf ZiemssenCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.ORCID 0000-0001-8799-8202
Katja AkgünCenter of Clinical Neuroscience, University Hospital Carl Gustav Carus, Dresden University of Technology, 01307 Dresden, Germany.ORCID 0000-0003-1371-5032
University Hospital Carl Gustav Carus · DERoche (Switzerland) · CH

Funding

Roche (Germany) Fonds Nr. 105.1067, PO Nr. EPBA2688985-A46
6 · The paper itself

Abstract

Our objective was to analyze longitudinal cellular and humoral immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in people with multiple sclerosis (pwMS) on B-cell depleting treatment (BCDT) compared to pwMS without immunotherapy. We further evaluated the impact of COVID-19 infection and vaccination timing. PwMS (

Indexed as

anti-CD20 therapyinterferon-gamma release assaymultiple sclerosisocrelizumabSARS-CoV-2vaccination

Identifiers

PMID37766140
PMCPMC10537223
OpenAlexW4386525434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.