Evidence map›Paper›PMID 37765676›Full record

ReviewPolymers2023

Synthetic Calcium-Phosphate Materials for Bone Grafting.

Oleg Mishchenko, Anna Yanovska, Oleksii Kosinov, Denys Maksymov, Roman Moskalenko, Arunas Ramanavicius, Maksym Pogorielov

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07638319 early_phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry

TypeinterventionalSponsorEgas Moniz - Cooperativa de Ensino Superior, CRLRan2025 to 2028Enrolled30ConditionsTooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone LossArmsNeocement Inject P® (Beta-Tricalcium Phosphate)
NCT07638358 early_phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Assessment of Safety and Performance of Neobone®: A Prospective Observational Study in the Field of Dentistry

TypeinterventionalSponsorEgas Moniz - Cooperativa de Ensino Superior, CRLRan2025 to 2028Enrolled30ConditionsTooth Extraction Site Healing, Alveolar Ridge PreservationArmsNeobone® (Biphasic Calcium Phosphate)
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 83 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Oleg MishchenkoDepartment of Surgical and Propaedeutic Dentistry, Zaporizhzhia State Medical and Pharmaceutical University, 26, Prosp. Mayakovskogo, 69035 Zaporizhzhia, Ukraine.ORCID 0000-0002-6378-7061
Anna YanovskaTheoretical and Applied Chemistry Department, Sumy State University, R-Korsakova Street, 40007 Sumy, Ukraine.ORCID 0000-0001-8040-7457
Oleksii KosinovDepartment of Surgical and Propaedeutic Dentistry, Zaporizhzhia State Medical and Pharmaceutical University, 26, Prosp. Mayakovskogo, 69035 Zaporizhzhia, Ukraine.
Denys MaksymovDepartment of Surgical and Propaedeutic Dentistry, Zaporizhzhia State Medical and Pharmaceutical University, 26, Prosp. Mayakovskogo, 69035 Zaporizhzhia, Ukraine.
Roman MoskalenkoDepartment of Pathology, Sumy State University, R-Korsakova Street, 40007 Sumy, Ukraine.ORCID 0000-0002-2342-0337
Arunas RamanaviciusNanoTechnas-Center of Nanotechnology and Materials Science, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, Lithuania.ORCID 0000-0002-0885-3556
Maksym PogorielovBiomedical Research Centre, Sumy State University, R-Korsakova Street, 40007 Sumy, Ukraine.ORCID 0000-0001-9372-7791
Sumy State University · UAZaporizhzhia State Medical and Pharmaceutical University · UAVilnius University · LT

Funding

European Commission Horizon Europe MSCA-2021-SE-01 ARGO #101086441Ministry of Education and Science of Ukraine 0121U100471National Research Foundation of Ukraine 2020.02/0223
6 · The paper itself

Abstract

Synthetic bone grafting materials play a significant role in various medical applications involving bone regeneration and repair. Their ability to mimic the properties of natural bone and promote the healing process has contributed to their growing relevance. While calcium-phosphates and their composites with various polymers and biopolymers are widely used in clinical and experimental research, the diverse range of available polymer-based materials poses challenges in selecting the most suitable grafts for successful bone repair. This review aims to address the fundamental issues of bone biology and regeneration while providing a clear perspective on the principles guiding the development of synthetic materials. In this study, we delve into the basic principles underlying the creation of synthetic bone composites and explore the mechanisms of formation for biologically important complexes and structures associated with the various constituent parts of these materials. Additionally, we offer comprehensive information on the application of biologically active substances to enhance the properties and bioactivity of synthetic bone grafting materials. By presenting these insights, our review enables a deeper understanding of the regeneration processes facilitated by the application of synthetic bone composites.

Indexed as

biopolymerscompositeshydroxyapatiteregenerative dentistrysynthetic bone materials

Identifiers

PMID37765676
PMCPMC10536599
OpenAlexW4386895014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.