Evidence map›Paper›PMID 37765026›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Tryptophan Substitution in CJ-15,208 (

Kristen H Scherrer, Shainnel O Eans, Jessica M Medina, Sanjeewa N Senadheera, Tanvir Khaliq, Thomas F Murray, Jay P McLaughlin, Jane V Aldrich

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kristen H ScherrerDepartment of Pharmacodynamics, The University of Florida, Gainesville, FL 32610, USA.
Shainnel O EansDepartment of Pharmacodynamics, The University of Florida, Gainesville, FL 32610, USA.
Jessica M MedinaDepartment of Pharmacodynamics, The University of Florida, Gainesville, FL 32610, USA.
Sanjeewa N SenadheeraDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, KS 66045, USA.ORCID 0000-0003-0798-1721
Tanvir KhaliqDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Thomas F MurrayDepartment of Pharmacology and Neuroscience, Creighton University School of Medicine, Omaha, NE 68178, USA.ORCID 0000-0001-8521-4507
Jay P McLaughlinDepartment of Pharmacodynamics, The University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0001-9851-9342
Jane V AldrichDepartment of Medicinal Chemistry, The University of Kansas, Lawrence, KS 66045, USA.ORCID 0000-0002-7954-9850
University of Florida · USUniversity of Kansas · USCreighton University · US

Funding

Development of Novel Opioid Peptides for Cocaine AbuseR01DA032928 · NIDA · UNIVERSITY OF KANSAS LAWRENCE · PI LUNTE, SUSAN M · 2012 to 2014
$2.1M
Cyclic Peptides to Treat Cocaine Use DisorderUG3NS132600 · NINDS · UNIVERSITY OF FLORIDA · PI ALDRICH, JANE V, BIDLACK, JEAN M · 2023 to 2023
$945k
NIDA NIH HHS R01 DA032928NIH HHS R01 DA03292NIH HHS UG3 NS132600NINDS NIH HHS UG3 NS132600
6 · The paper itself

Abstract

The macrocyclic tetrapeptide CJ-15,208 (

Indexed as

analgesicsdelta opioid receptorkappa opioid receptormacrocyclic tetrapeptidesmetabolic stabilitymultifunctional ligandsopioid liabilitiesopioid peptidesstructure–activity relationships

Identifiers

PMID37765026
PMCPMC10535824
OpenAlexW4386246279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.