Evidence map›Paper›PMID 37764996›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Synergistic Effect of Ginsenoside Rh2 Combines with Ionizing Radiation on CT26/

Shan-Chih Lee, Chao-Yu Shen, Wei-Hsun Wang, Yen-Po Lee, Keng-Wei Liang, Ying-Hsiang Chou, Yeu-Sheng Tyan, Jeng-Jong Hwang

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Anti-Colorectal Cancer Activity ofInternational journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shan-Chih LeeDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.ORCID 0000-0001-6583-1575
Chao-Yu ShenDepartment of Medical Imaging, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.ORCID 0000-0003-3571-0697
Wei-Hsun WangDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua 50044, Taiwan.
Yen-Po LeeDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei Branch, Hsinchu City 30010, Taiwan.
Keng-Wei LiangDepartment of Medical Imaging, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.ORCID 0000-0001-9124-4737
Ying-Hsiang ChouDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.ORCID 0000-0001-5888-4302
Yeu-Sheng TyanDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.
Jeng-Jong HwangDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.ORCID 0000-0002-3847-4426
Chung Shan Medical University Hospital · TWChanghua Christian Hospital · TWChung Shan Medical University · TWNational Yang Ming Chiao Tung University · TW

Funding

Chung Shan Medical University Hospital, Taichung, Taiwan. CSH-2020-C-024
6 · The paper itself

Abstract

backgroundThe local tumor control rate of colon cancer by radiotherapy is unsatisfactory due to recurrence and radioresistance. Ginsenoside Rh2 (Rh2), a panoxadiol saponin, possesses various antitumor effects.

methodsCT26/

resultsRh2 caused cell cycle arrest at the G1 phase in CT26/

conclusionsThe combination of Rh2 with radiation may have potential as an alternative to improve the therapeutic efficacy of colorectal cancer.

Indexed as

colorectal cancerginsenoside Rh2immunomodulationradiotherapy

Identifiers

PMID37764996
PMCPMC10535731
OpenAlexW4386051149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.