Evidence map›Paper›PMID 37764925›Full record

ReviewPathogens (Basel, Switzerland)2023

Rabbits as Animal Models for Anti-Tick Vaccine Development: A Global Scenario.

Arlex Rodríguez-Durán, Shafi Ullah, Luís Fernando Parizi, Abid Ali, Itabajara da Silva Vaz Junior

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Arlex Rodríguez-DuránCentro de Biotecnologia, Universidade Federal do Rio Grande de Sul, Avenida Bento Gonçalves, 9500, Porto Alegre 91501-970, RS, Brazil.ORCID 0000-0001-7827-2215
Shafi UllahCentro de Biotecnologia, Universidade Federal do Rio Grande de Sul, Avenida Bento Gonçalves, 9500, Porto Alegre 91501-970, RS, Brazil.ORCID 0000-0002-3404-1690
Luís Fernando PariziCentro de Biotecnologia, Universidade Federal do Rio Grande de Sul, Avenida Bento Gonçalves, 9500, Porto Alegre 91501-970, RS, Brazil.
Abid AliDepartment of Zoology, Abdul Wali Khan University Mardan, Mardan 23200, Khyber Pakhtunkhwa, Pakistan.ORCID 0000-0001-6411-6625
Itabajara da Silva Vaz JuniorCentro de Biotecnologia, Universidade Federal do Rio Grande de Sul, Avenida Bento Gonçalves, 9500, Porto Alegre 91501-970, RS, Brazil.ORCID 0000-0003-0309-9328
Universidade Federal do Rio Grande · BRAbdul Wali Khan University Mardan · PK

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88881.068421/2014-01Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/210.012/2018Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro SEI-260003/001743/2023Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul 21/2551-0002221-3Ministerio de Ciencia Tecnología e Innovación de Colombia 885/2020National Council for Scientific and Technological Development 465678/2014-9
6 · The paper itself

Abstract

Studies evaluating candidate tick-derived proteins as anti-tick vaccines in natural hosts have been limited due to high costs. To overcome this problem, animal models are used in immunization tests. The aim of this article was to review the use of rabbits as an experimental model for the evaluation of tick-derived proteins as vaccines. A total of 57 tick proteins were tested for their immunogenic potential using rabbits as models for vaccination. The most commonly used rabbit breeds were New Zealand (73.8%), Japanese white (19%), Californians (4.8%) and Flemish lop-eared (2.4%) rabbits. Anti-tick vaccines efficacy resulted in up to 99.9%.

Indexed as

Arthropod ProteinsTick InfestationsTicksVaccine DevelopmentVaccinesAnimalsDisease Models, AnimalRabbitsVaccinationArthropod ProteinsVaccinesantigenhumoral and adaptive responseimmunizationrabbittick

Identifiers

PMID37764925
PMCPMC10536012
OpenAlexW4386380384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.