ArticleNutrients2023
Association between Dietary Choline Intake and Cardiovascular Diseases: National Health and Nutrition Examination Survey 2011-2016.
Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Dietary Choline and Betaine Are Not Associated With the Risk of Type 2 Diabetes. A Systematic Review and Meta-Analysis of Observational Studies.Journal of diabetes research · 2026Pooled it
- Choline status and related health outcomes in humans: A scoping review.Nutrition and health · 2026Article
- Development of a Choline Database for Thai Food and a Population-Wide Assessment of Choline Intake in Thailand.Nutrients · 2026Article
- The essential role of hydrogen gas recycling by gut microbes in reducing deuterium load in host mitochondria: is trimethylamine oxide a deuterium sensor?Metabolomics : Official journal of the Metabolomic Society · 2026Review
- Metabolic Signatures of Air Pollution and Major Adverse Cardiovascular Events in Patients Undergoing Cardiac Catheterization.JACC. Advances · 2026Article
- Nutritional Aspects of Eggs for a Healthy and Sustainable Consumption: A Narrative Review.Food science & nutrition · 2025Review
- Comparison of two measurement error-correction approaches for assessing the association between choline intake and coronary heart disease prevalence among US community-dwelling adults.Annals of epidemiology · 2025Article
- Association between neutrophil percentage to albumin ratio and cardiovascular disease in the metabolic syndrome population.Scientific reports · 2025Article
- Association of Dietary Choline Intake With Incidence of Frailty: A Nationwide Prospective Cohort Study From China.Journal of cachexia, sarcopenia and muscle · 2025Article
- Egg Consumption and Mortality: A Prospective Cohort Study of Australian Community-Dwelling Older Adults.Nutrients · 2025Article
- Sleep Patterns and Cardiovascular Disease Risk: Investigating the Mediating Role of Inflammatory Markers in a Large NHANES Adult Population.Mediators of inflammation · 2025Article
- Choline in immunity: a key regulator of immune cell activation and function.Frontiers in immunology · 2025Review
- Dietary choline intake in European and non-european populations: current status and future trends-a narrative review.Nutrition journal · 2024Review
- The Interplay Between Dietary Choline and Cardiometabolic Disorders: A Review of Current Evidence.Current nutrition reports · 2024Review
- Causal relationship between nutritional assessment phenotypes and heart failure: A Mendelian randomization study.Heliyon · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Choline is an essential nutrient for human body, but dietary choline is metabolized into the hazard metabolite for the cardiovascular system. Because of the conflicting results between dietary choline intake and cardiovascular disease (CVD) risk in previous studies, we aimed to investigate this in US adults. Non-pregnant participants and those aged >20 years from National Health and Nutrition Examination Survey 2011-2016, with CVD assessment and reliable dietary recall status, were included. The dietary choline intake was assessed as a mean value of two total dietary choline intakes, including dietary choline intake and supplemental choline intake, in 24-h dietary recall interviews. The association between dietary choline intake and the presence of CVD was examined using logistic regression. We enrolled 14,323 participants. The participants without CVD had substantially higher dietary choline intakes (318.4 mg/d vs. 297.2 mg/d) compared to those with CVD (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.