Evidence map›Paper›PMID 37764799›Full record

ArticleNutrients2023

Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in

Helen Holvoet, Dani M Long, Liping Yang, Jaewoo Choi, Luke Marney, Burkhard Poeck, Claudia S Maier, Amala Soumyanath, Doris Kretzschmar, Roland Strauss

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Frontiers in aging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Helen HolvoetInstitut für Entwicklungsbiologie und Neurobiologie, Johannes Gutenberg-Universität Mainz, 55128 Mainz, Germany.
Dani M LongBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Liping YangBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Jaewoo ChoiBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Luke MarneyBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Burkhard PoeckInstitut für Entwicklungsbiologie und Neurobiologie, Johannes Gutenberg-Universität Mainz, 55128 Mainz, Germany.
Claudia S MaierBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Amala SoumyanathBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0003-1569-6453
Doris KretzschmarBENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.
Roland StraussInstitut für Entwicklungsbiologie und Neurobiologie, Johannes Gutenberg-Universität Mainz, 55128 Mainz, Germany.
Oregon State University · USJohannes Gutenberg University Mainz · DEOregon Health & Science University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Mechanisms underlying the cognitive effects of Centella asiatica water extract and constituent compounds in the 5xFAD mouse model of Alzheimer's DiseaseU19AT010829 · NCCIH · OREGON HEALTH & SCIENCE UNIVERSITY · PI SOUMYANATH, AMALA · 2020 to 2024
$6.1M
Ultra-Performance Liquid Chromatography Tandem Quadrupole Mass Spectrometry SystemS10OD026922 · OD · OREGON STATE UNIVERSITY · PI MAIER, CLAUDIA S · 2019 to 2019
$577k
NCCIH NIH HHS U19 AT010829NCCIH NIH HHS U19AT010829NIH HHS P40 OD018537NIH HHS S10 OD026922
6 · The paper itself

Abstract

Common symptoms of depressive disorders include anhedonia, sleep problems, and reduced physical activity. Drugs used to treat depression mostly aim to increase serotonin signaling but these can have unwanted side effects. Depression has also been treated by traditional medicine using plants like

Indexed as

CentellaResilience, PsychologicalTriterpenesAnhedoniaAnimalsCalcineurinChlorogenic AcidDrosophila melanogasterPlant ExtractsCalcineurinChlorogenic AcidPlant ExtractsTriterpenesanhedoniacaffeoylquinic acidschronic stressGotu Kolatriterpenes

Identifiers

PMID37764799
PMCPMC10537055
OpenAlexW4386838474

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.