Evidence map›Paper›PMID 37764737›Full record

ReviewNutrients2023

Autoimmune Thyroid Disorders: The Mediterranean Diet as a Protective Choice.

Rosaria Maddalena Ruggeri, Maria Cristina Barbalace, Laura Croce, Marco Malaguti, Alfredo Campennì, Mario Rotondi, Salvatore Cannavò, Silvana Hrelia

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 42 citations in OpenAlex.

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  9. The role of nutrition on thyroid health and disease: myths and facts.Journal of endocrinological investigation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rosaria Maddalena RuggeriDepartment of Human Pathology of Adulthood and Childhood DETEV "G. Barresi", Endocrinology Unit, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-8899-684X
Maria Cristina BarbalaceDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-5686-0470
Laura CroceDepartment of Internal Medicine and Therapeutics, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) University of Pavia, 27100 Pavia, Italy.
Marco MalagutiDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-0349-7772
Alfredo CampennìDepartment of Biomedical and Dental Sciences and Morpho-Functional Imaging, Unit of Nuclear Medicine, University of Messina, 98125 Messina, Italy.ORCID 0000-0002-0177-939X
Mario RotondiDepartment of Internal Medicine and Therapeutics, Unit of Endocrinology and Metabolism, Laboratory for Endocrine Disruptors, Istituti Clinici Scientifici Maugeri, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) University of Pavia, 27100 Pavia, Italy.
Salvatore CannavòDepartment of Human Pathology of Adulthood and Childhood DETEV "G. Barresi", Endocrinology Unit, University of Messina, 98125 Messina, Italy.ORCID 0000-0001-8779-7283
Silvana HreliaDepartment for Life Quality Studies, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-7857-4512
University of Bologna · ITUniversity of Messina · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune thyroid diseases are on the rise worldwide, and such a rapid increase is mainly driven by environmental factors related to changed lifestyles in "modern" societies. In this context, diet seems to play a crucial role. An unhealthy high-energy diet, rich in animal fat and proteins, salt and refined sugars (the so-called "Western diet") negatively influences the risk of autoimmunity by altering the immune balance and the gut microbiota composition, enhancing oxidative stress and promoting inflammation. In contrast, the Mediterranean diet represents a unique model of healthy eating, characterized by a high intake of food from vegetable sources, a low consumption of saturated fats in favor of unsaturated fats (mainly, olive oil), a moderate consumption of fish (typically, the small oily fishes) and dairy products, as well as a moderate consumption of wine at meals, and a low intake of meat. Thanks to its nutritional components, the Mediterranean Diet positively influences immune system function, gut microbiota composition, and redox homeostasis, exerting anti-oxidants, anti-inflammatory, and immunomodulatory effects. The present review was aimed at exploring the existing knowledge on the correlations between dietary habits and thyroid autoimmunity, to evaluate the role of the Mediterranean diet as a protective model.

Indexed as

Autoimmune DiseasesDiet, MediterraneanThyroid DiseasesThyroiditis, AutoimmuneDiet, HealthyGastrointestinal MicrobiomeHumansautoimmune thyroid diseasesHashimoto’s thyroiditisMediterranean dietoxidative stressvegetarianismWestern diet

Identifiers

PMID37764737
PMCPMC10535745
OpenAlexW4386629090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.