Evidence map›Paper›PMID 37764705›Full record

ArticleNutrients2023

The Need for Culturally Appropriate Food Allergy Management Strategies: The Indian Milk Ladder.

Somashekara Hosaagrahara Ramakrishna, Neil Shah, Bhaswati C Acharyya, Emmany Durairaj, Lalit Verma, Srinivas Sankaranarayanan, Nishant Wadhwa, Carina Venter

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Characterizing detectable milk protein allergens β-casein and β-lactoglobulin in milk ladder foods.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Somashekara Hosaagrahara RamakrishnaDepartment of Paediatric Hepatology & Gastroenterology, Gleneagles Global Health City, Chennai 600100, India.ORCID 0000-0001-8846-1212
Neil ShahThe Portland Hospital, London W1W 5AH, UK.
Bhaswati C AcharyyaDepartment of Paediatric Hepatology & Gastroenterology, AMRI Hospitals, Kolkata 700028, India.
Emmany DurairajDepartment of Clinical Nutrition, Mazumdar Shaw Medical Centre, Narayana Health City, Bengaluru 560099, India.
Lalit VermaDepartment of Paediatric Hepatology & Gastroenterology, Global Hospitals, Mumbai 400012, India.
Srinivas SankaranarayananDepartment of Paediatric Hepatology & Gastroenterology, Kanchi Kamakoti CHILDS Trust Hospital, Chennai 600024, India.
Nishant WadhwaInstitute of Child Health, Division of Paediatric Gastroenterology, Hepatology & Nutrition, Sir Gangaram Hospital, New Delhi 110060, India.
Carina VenterPaediatrics, Section of Allergy & Immunology, Denver School of Medicine, University of Colorado, Denver, CO 80204, USA.
Apollo Hospitals · INChildren's Hospital Colorado · USGlobal Hospitals · INInstitute of Child Health · INNarayana Health · INReckitt Benckiser (United Kingdom) · GBSir Ganga Ram Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCow's milk allergy (CMA) is one of the most common and complex food allergies affecting children worldwide and, with a few exceptions, presents in the first few months of life. Baked-milk-containing diets are well tolerated in the majority of milk-allergic children and allow dietary restrictions to be relaxed. In addition, the early introduction of tolerated forms of allergenic foods to an infant's diet in small amounts may enhance the outgrowth of their milk allergy through oral tolerance induction. The methods of milk introduction vary widely across the globe.

methodsWe convened an expert group to develop a comprehensive milk ladder based on the calculated milk protein content of Indian foods. To validate the milk ladder, the foods chosen for the ladder were analyzed and the ladder was re-evaluated based on the cooked milk protein content.

resultsCombining expert consensus and validation of milk protein content, we created the world's first milk ladder containing Indian foods. This is the first ladder that provides information on the timing and temperature of cooking, with validated milk protein content.

conclusionsThis is the first milk ladder based on the unique features of Indian food habits built by the consensus of Indian experts along with international collaboration with laboratory quantification of milk protein in each step. We believe the "The Indian Milk Ladder" will be a very helpful tool for pediatricians helping manage CMA in children as well as their parents and caregivers, not only in India, but in countries world-wide where these foods are commonly consumed.

Indexed as

Food HypersensitivityMilk HypersensitivityAnimalsCattleChildColostrumFemaleHumansInfantMilkMilk ProteinsPregnancyMilk Proteinsbaked foodCMAcow’s milk allergymilk laddertolerance acquisition

Identifiers

PMID37764705
PMCPMC10535525
OpenAlexW4386601959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.