Evidence map›Paper›PMID 37764526›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Construction of Metal Organic Framework-Derived Fe-N-C Oxidase Nanozyme for Rapid and Sensitive Detection of Alkaline Phosphatase.

Mengmeng Pan, Ming Wang, Linjiao Yang, Yongli Song, Ming Jiang, Xu Yu, Li Xu

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Nanozymes Integrated Biochips Toward Smart Detection System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Biomedical Applications of Metal-Organic Frameworks Revisited.Industrial & engineering chemistry research · 2025
    Review
  4. Nanosomes in Precision Nanomedicine.Nanomaterials (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mengmeng PanTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-3969-6346
Ming WangDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0002-2836-1217
Linjiao YangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.
Yongli SongTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.
Ming JiangTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-1999-1866
Xu YuTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-3587-7019
Li XuTongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.
Huazhong University of Science and Technology · CNWuhan University · CN

Funding

Fundamental Research Funds for the Central Universities in China 2019kfyRCPY112, 2020kfyXJJS082National Natural Science Foundation of China 21804105, 22174049Natural Science Foundation of Hubei Province of China 2021CFB335Program for HUST Academic Frontier Youth Team 2019QYTD09
6 · The paper itself

Abstract

Alkaline phosphatase (ALP) is a phosphomonoester hydrolase and serves as a biomarker in various diseases. However, current detection methods for ALP rely on bulky instruments, extended time, and complex operations, which are particularly challenging in resource-limited regions. Herein, we synthesized a MOF-derived Fe-N-C nanozyme to create biosensors for the coulometric and visual detection of ALP. Specifically, we found the Fe-N-C nanozyme can efficiently oxidize 3,3',5,5'-tetramethylbenzidine (TMB) to generate blue-colored tetramethyl benzidine (TMB

Indexed as

alkaline phosphatasemetal-organic frameworknanozymeoxidase-like enzymevisual detection

Identifiers

PMID37764526
PMCPMC10537703
OpenAlexW4386461407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.