Evidence map›Paper›PMID 37764475›Full record

ReviewMolecules (Basel, Switzerland)2023

Advances in 4-Hydroxyphenylacetate-3-hydroxylase Monooxygenase.

Kai Yang, Qianchao Zhang, Weirui Zhao, Sheng Hu, Changjiang Lv, Jun Huang, Jiaqi Mei, Lehe Mei

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Efficient synthesis of l-DOPA inSynthetic and systems biotechnology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kai YangDepartment of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Qianchao ZhangSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Weirui ZhaoSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Sheng HuSchool of Biological and Chemical Engineering, Ningbo Tech University, Ningbo 315100, China.
Changjiang LvDepartment of Chemical and Biological Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Jun HuangDepartment of Chemical and Biological Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, China.
Jiaqi MeiHangzhou Huadong Medicine Group Co., Ltd., Hangzhou 310011, China.
Lehe MeiDepartment of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310027, China.
Ningbo University of Technology · CNZhejiang University of Science and Technology · CNJinhua Academy of Agricultural Sciences · CN

Funding

National Natural Science Foundation of China 32071268, 31971372Zhejiang Natural Science Foundation LY21B060003, LY23B060001
6 · The paper itself

Abstract

Catechols have important applications in the pharmaceutical, food, cosmetic, and functional material industries. 4-hydroxyphenylacetate-3-hydroxylase (4HPA3H), a two-component enzyme system comprising HpaB (monooxygenase) and HpaC (FAD oxidoreductase), demonstrates significant potential for catechol production because it can be easily expressed, is highly active, and exhibits

Indexed as

CatecholsMixed Function OxygenasesPhenylacetates4-hydroxyphenylacetatecatecholCatecholsMixed Function OxygenasesPhenylacetates4-hydroxyphenylacetate-3-hydroxylase monooxygenasebiocatalysiscatecholsprotein engineeringstructural property

Identifiers

PMID37764475
PMCPMC10537072
OpenAlexW4386893720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.