Evidence map›Paper›PMID 37764464›Full record

ArticleMolecules (Basel, Switzerland)2023

Optimization of the Green Extraction of Red Araçá (

Douglas Hardt Lacorte, Alaor Valério Filho, Márcio Dantas Carvalho, Luisa Bataglin Avila, Caroline Costa Moraes, Gabriela Silveira da Rosa

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Douglas Hardt LacorteGraduate Program in Science and Engineering of Materials, Federal University of Pampa, Bagé 96413-172, Brazil.
Alaor Valério FilhoGraduate Program in Materials Science and Engineering, Technology Development Center, Federal University of Pelotas, Pelotas 96010-610, Brazil.
Márcio Dantas CarvalhoChemical Engineering, Federal University of Pampa, Bagé 96413-172, Brazil.
Luisa Bataglin AvilaDepartment of Chemical Engineering, Federal University of Santa Maria, Santa Maria 97105-900, Brazil.
Caroline Costa MoraesGraduate Program in Science and Engineering of Materials, Federal University of Pampa, Bagé 96413-172, Brazil.ORCID 0000-0003-0467-1015
Gabriela Silveira da RosaGraduate Program in Science and Engineering of Materials, Federal University of Pampa, Bagé 96413-172, Brazil.ORCID 0000-0002-8831-448X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this research, the aim was to introduce innovation to the pharmaceutical field through the exploration of an underutilized plant matrix, the red araçá, along with the utilization of sodium alginate for the development of membranes designed for active topical dressings. Within this context, optimal extraction conditions were investigated using the central composite rotational statistical design (CCRD) to obtain a red araçá epicarp extract (RAEE) rich in bioactive compounds utilizing the maceration technique. The extract acquired under the optimized conditions (temperature of 66 °C and a hydroalcoholic solvent concentration of 32%) was incorporated into a sodium alginate matrix for the production of active membranes using a casting method. Characterization of the membranes revealed that the addition of the extract did not significantly alter its morphology. Furthermore, satisfactory results were observed regarding mechanical and barrier properties, as well as the controlled release of phenolic compounds in an environment simulating wound exudate. Based on these findings, the material produced from renewable matrices demonstrates the promising potential for application as a topical dressing within the pharmaceutical industry.

Indexed as

AlginatesBandagesMembranes, ArtificialPlant ExtractsPsidiumGreen Chemistry TechnologyAlginatesMembranes, ArtificialPlant Extractsbioactive compoundsbiopolymerskin lesion

Identifiers

PMID37764464
PMCPMC10537386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.