Evidence map›Paper›PMID 37764416›Full record

ReviewMolecules (Basel, Switzerland)2023

Drug Discovery Based on Fluorine-Containing Glycomimetics.

Xingxing Wei, Pengyu Wang, Fen Liu, Xinshan Ye, Decai Xiong

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Synthetic Access to Fluorinated Analogs of a KnownACS organic & inorganic Au · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Synthesis of Fluorinated Glycotope Mimetics Derived fromInternational journal of molecular sciences · 2025
    Article
  9. The Journal of organic chemistry · 2024
    Article
  10. Article
  11. Glycomimetics and Glycoconjugates in Drug Discovery.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  12. Monofluoromethylation ofInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xingxing WeiDepartment of Pharmacy, Changzhi Medical College, No. 161, Jiefang East Street, Changzhi 046012, China.
Pengyu WangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. No. 38, Beijing 100191, China.
Fen LiuState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. No. 38, Beijing 100191, China.
Xinshan YeState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. No. 38, Beijing 100191, China.
Decai XiongState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd. No. 38, Beijing 100191, China.ORCID 0000-0002-5187-9313
Peking University · CNChangzhi Medical College · CN

Funding

the National Natural Science Foundation of China Nos. 21977003, 22007003
6 · The paper itself

Abstract

Glycomimetics, which are synthetic molecules designed to mimic the structures and functions of natural carbohydrates, have been developed to overcome the limitations associated with natural carbohydrates. The fluorination of carbohydrates has emerged as a promising solution to dramatically enhance the metabolic stability, bioavailability, and protein-binding affinity of natural carbohydrates. In this review, the fluorination methods used to prepare the fluorinated carbohydrates, the effects of fluorination on the physical, chemical, and biological characteristics of natural sugars, and the biological activities of fluorinated sugars are presented.

Indexed as

Drug DiscoveryFluorineBiological AvailabilityCarbohydratesHalogenationSugarsCarbohydratesFluorineSugarsdrug discoveryfluorinationglycomimeticsphysical propertiessynthesis

Identifiers

PMID37764416
PMCPMC10536126
OpenAlexW4386838644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.