ArticleMicroorganisms2023
Bacteremia in Patients with Sepsis in the ICU: Does It Make a Difference?
Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Association between blood culture positivity and in-hospital mortality in pediatric oncology patients with sepsis in the PICU: a retrospective cohort analysis.Frontiers in cellular and infection microbiology · 2026Article
- Machine learning for prediction of in-ICU mortality in sepsis: an observational study using the MIMIC IV database.Archives of medical science : AMS · 2026Article
- Long-term outcomes of ICU-acquired infections with a focus on bloodstream infections: a single-center retrospective registry study.Infection · 2025Article
- The predictive performance of NEWS, MEWS, SOFA and SAPS II in outcomes of bacteremic and non-bacteremic sepsis.BMC infectious diseases · 2025Observational
- Blood culture positive sepsis in England, 2017-2018: epidemiological assessment of the commissioning for quality and innovation (CQUIN) sepsis indicator.BMC infectious diseases · 2025Article
- PBPK/PD Model of Vancomycin in Sepsis: Linking Interstitial Exposure in Perfusion-Limited Tissues to MRSA Infection.Pharmaceutics · 2025Article
- Impact of blood culture positivity on clinical outcomes in sepsis: a prospective observational study.Le infezioni in medicina · 2025Article
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Authors and funding
5 authors.
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Abstract
Sepsis (and septic shock) is on of the most common causes of death worldwide. Bacteremia often, but not necessarily, occurs in septic patients, but the impact of true bacteremia on a patient's clinical characteristics and outcome remains unclear. The main aim of this study was to compare the characteristics and outcome of a well-defined cohort of 258 septic patients with and without bacteremia treated in the intensive care unit (ICU) of a tertiary center hospital in Prague, Czech Republic. As expected, more frequently, bacteremia was present in patients without previous antibiotic treatment. A higher proportion of bacteremia was observed in patients with infective endocarditis as well as catheter-related and soft tissue infections in contrast to respiratory sepsis. Multivariant analysis showed increased severity of clinical status and higher Charlson comorbidity index (CCI) as variables with significant influence on mortality. Bacteremia appears to be associated with higher mortality rates and length of ICU stay in comparison with nonbacteremic counterparts, but this difference did not reach statistical significance. The presence of bacteremia, apart from previous antibiotic treatment, may be related to the site of infection.
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