Evidence map›Paper›PMID 37764129›Full record

ArticleMicroorganisms2023

The Association between Gut Microbiota and Depression in the Japanese Population.

Yichi Yang, Mone Mori, Kyi Mar Wai, Tao Jiang, Yoshikuni Sugimura, Wataru Munakata, Tatsuya Mikami, Koichi Murashita, Shigeyuki Nakaji, Kazushige Ihara

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. International journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yichi YangDepartment of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Mone MoriSchool of Medicine, Hirosaki University, Hirosaki 036-8562, Japan.
Kyi Mar WaiDepartment of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0001-8755-277X
Tao JiangDepartment of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Yoshikuni SugimuraDepartment of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.
Wataru MunakataDepartment of Hematology, National Cancer Center Hospital, Tokyo 104-0045, Japan.
Tatsuya MikamiInnovation Center for Health Promotion, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0002-6657-6446
Koichi MurashitaCenter of Innovation Research Initiatives Organization, Hirosaki University, Hirosaki 036-8562, Japan.
Shigeyuki NakajiDepartment of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.ORCID 0000-0002-4190-5151
Kazushige IharaDepartment of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a leading cause of disease worldwide. The association between gut microbiota and depression has barely been investigated in the Japanese population. We analyzed Iwaki health check-up data collected from 2017 to 2019 and constructed generalized linear mixed models. The independent variable was the relative abundance of each of the 37 gut microbiota genera that were reported to be associated with depression. The dependent variable was the presence of depression assessed by the Center for Epidemiologic Studies Depression Scale. Potential confounders, including grip strength, gender, height, weight, smoking, and drinking habits, were adjusted in the regression models. Nine genera's regression coefficients (

Indexed as

gut bacteriagut–brain axisinterleukin-6mental disorder

Identifiers

PMID37764129
PMCPMC10534301

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.