Evidence map›Paper›PMID 37764092›Full record

ReviewMicroorganisms2023

Molecular Mechanisms of Persistence in Protozoan Parasites.

Asfiha Tarannum, Cristian Camilo Rodríguez-Almonacid, Jorge Salazar-Bravo, Zemfira N Karamysheva

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Persistence of protozoan parasites andApplied and environmental microbiology · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Molecular Mechanisms of Drug Resistance inPathogens (Basel, Switzerland) · 2024
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Asfiha TarannumDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Cristian Camilo Rodríguez-AlmonacidDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
Jorge Salazar-BravoDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0001-5905-2532
Zemfira N KaramyshevaDepartment of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0002-1589-0216
Texas Tech University · US

Funding

Ribosome remodeling as a mechanism of translational control during stressR15GM146171 · NIGMS · TEXAS TECH UNIVERSITY · PI SALAZAR-BRAVO, JORGE · 2022 to 2023
$559k
NIGMS NIH HHS R15 GM146171NIGMS NIH HHS R15GM146171
6 · The paper itself

Abstract

Protozoan parasites are known for their remarkable capacity to persist within the bodies of vertebrate hosts, which frequently results in prolonged infections and the recurrence of diseases. Understanding the molecular mechanisms that underlie the event of persistence is of paramount significance to develop innovative therapeutic approaches, given that these pathways still need to be thoroughly elucidated. The present article provides a comprehensive overview of the latest developments in the investigation of protozoan persistence in vertebrate hosts. The focus is primarily on the function of persisters, their formation within the host, and the specific molecular interactions between host and parasite while they persist. Additionally, we examine the metabolomic, transcriptional, and translational changes that protozoan parasites undergo during persistence within vertebrate hosts, focusing on major parasites such as

Indexed as

Apicomplexametabolomeprotozoa persisterstranslatome

Identifiers

PMID37764092
PMCPMC10534552
OpenAlexW4386498338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.