Evidence map›Paper›PMID 37764061›Full record

ReviewMicroorganisms2023

The Maternal Microbiome and Gestational Diabetes Mellitus: Cause and Effect.

Stephanie Dias, Carmen Pheiffer, Sumaiya Adam

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07446205 (Poi for Mama), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07446205 narecruitingnot on this mapstarted 2026, after this paper: background citation

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

TypeinterventionalSponsorUniversity of HawaiiRan2026 to 2027Enrolled50ConditionsGestational Diabetes Mellitus (GDM), PregnancyArmsFermented Poi
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  12. Review
  13. Article
  14. Article
  15. Gestational age and models for predicting gestational diabetes mellitus.Metabolomics : Official journal of the Metabolomic Society · 2025
    Observational
  16. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stephanie DiasBiomedical Research and Innovation Platform (BRIP), South African Medical Research Council, Tygerberg, Cape Town 7505, South Africa.ORCID 0000-0003-3008-4279
Carmen PheifferBiomedical Research and Innovation Platform (BRIP), South African Medical Research Council, Tygerberg, Cape Town 7505, South Africa.ORCID 0000-0002-0707-1552
Sumaiya AdamDepartment of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, University of Pretoria, Pretoria 0028, South Africa.ORCID 0000-0001-8769-3273
South African Medical Research Council · ZAUniversity of Pretoria · ZA

Funding

National Research Foundation 129844South African Medical Research Council Baseline funding
6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is a growing public health concern that affects many pregnancies globally. The condition is associated with adverse maternal and neonatal outcomes including gestational hypertension, preeclampsia, placental abruption, preterm birth, stillbirth, and fetal growth restriction. In the long-term, mothers and children have an increased risk of developing metabolic diseases such as type 2 diabetes and cardiovascular disease. Accumulating evidence suggest that alterations in the maternal microbiome may play a role in the pathogenesis of GDM and adverse pregnancy outcomes. This review describes changes in the maternal microbiome during the physiological adaptations of pregnancy, GDM and adverse maternal and neonatal outcomes. Findings from this review highlight the importance of understanding the link between the maternal microbiome and GDM. Furthermore, new therapeutic approaches to prevent or better manage GDM are discussed. Further research and clinical trials are necessary to fully realize the therapeutic potential of the maternal microbiome and translate these findings into clinical practice.

Indexed as

adverse maternal outcomesadverse neonatal outcomesgestational diabetes mellitusmaternal microbiomepregnancy complications

Identifiers

PMID37764061
PMCPMC10535124
OpenAlexW4386371807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.