Evidence map›Paper›PMID 37764019›Full record

ArticleMicroorganisms2023

Improvements in Gut Microbiome Composition Predict the Clinical Efficacy of a Novel Synbiotics Formula in Children with Mild to Moderate Atopic Dermatitis.

Chi Tung Choy, Pui Ling Kella Siu, Junwei Zhou, Chi Ho Wong, Yuk Wai Lee, Ho Wang Chan, Joseph Chi Ching Tsui, Claudia Jun Yi Lo, Steven King Fan Loo, Stephen Kwok Wing Tsui

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chi Tung ChoyMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Pui Ling Kella SiuMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Junwei ZhouMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Chi Ho WongMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Yuk Wai LeeMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Ho Wang ChanMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Joseph Chi Ching TsuiMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Claudia Jun Yi LoMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Steven King Fan LooMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.
Stephen Kwok Wing TsuiMicrobiome Research Centre, BioMed Laboratory Company Limited, Hong Kong.ORCID 0000-0003-0686-4259
Chinese University of Hong Kong · HK

Funding

Hong Kong Society of Gut Microbiome N/A
6 · The paper itself

Abstract

Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a significant association with various type-2 inflammation-related comorbidities. Ongoing research suggests the crucial involvement of gut microbiome, especially in childhood onset AD, and hence, probiotics have emerged as a potential non-steroid-based therapeutics option to complement existing AD management plans. In order to delineate the impact of probiotics in the gut microbiome of pediatric AD patients from southern China, targeted 16S rRNA sequencing and thorough bioinformatic analysis were performed to analyze the gut microbiome profiles of 24 AD children after taking an orally administered novel synbiotics formula with triple prebiotics for 8 weeks. A notable improvement in Eczema Area and Severity Index (EASI) (

Indexed as

atopic dermatitisgut microbiomeprobiotics

Identifiers

PMID37764019
PMCPMC10536305
OpenAlexW4386254907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.