Evidence map›Paper›PMID 37764002›Full record

ArticleMicroorganisms2023

In Vitro Susceptibility to Ceftazidime-Avibactam and Comparator Antimicrobial Agents of Carbapenem-Resistant Enterobacterales Isolates.

Tze-Peng Lim, Jun-Yuan Ho, Jocelyn Qi-Min Teo, James Heng-Chiak Sim, Si-Hui Tan, Thuan-Tong Tan, Andrea Lay-Hoon Kwa

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tze-Peng LimDepartment of Pharmacy, Singapore General Hospital, 10 Hospital Boulevard, Singapore 168582, Singapore.ORCID 0000-0003-0610-687X
Jun-Yuan HoDepartment of Pharmacy, Singapore General Hospital, 10 Hospital Boulevard, Singapore 168582, Singapore.
Jocelyn Qi-Min TeoDepartment of Pharmacy, Singapore General Hospital, 10 Hospital Boulevard, Singapore 168582, Singapore.
James Heng-Chiak SimSingHealth Duke-NUS Pathology Academic Clinical Programme, 20 College Road, Singapore 169856, Singapore.
Si-Hui TanDepartment of Pharmacy, Singapore General Hospital, 10 Hospital Boulevard, Singapore 168582, Singapore.
Thuan-Tong TanSingHealth Duke-NUS Medicine Academic Clinical Programme, 10 Hospital Boulevard, Singapore 168582, Singapore.
Andrea Lay-Hoon KwaDepartment of Pharmacy, Singapore General Hospital, 10 Hospital Boulevard, Singapore 168582, Singapore.
Singapore General Hospital · SG

Funding

National Medical Research Council CG21APR1011National Medical Research Council CG21APR2005National Medical Research Council MOH-000018-00National Medical Research Council MOH-001168-01Pfizer Inc, NY, USA WI230757Pfizer Inc, NY, USA WI230776
6 · The paper itself

Abstract

The emergence of carbapenem-resistant Enterobacterales (CRE) has been recognized as a significant concern globally. Ceftazidime/avibactam (CZA) is a novel β-lactam/β-lactamase inhibitor that has demonstrated activity against isolates producing class A, C, and D β-lactamases. Here-in, we evaluated the in vitro activity of CZA and comparator antimicrobial agents against 858 CRE isolates, arising from the Southeast Asian region, collected from a large tertiary hospital in Singapore. These CRE isolates mainly comprised

Indexed as

antibiotic susceptibilitycarbapenemaseceftazidime/avibactamCREminimum inhibitory concentrations

Identifiers

PMID37764002
PMCPMC10534512
OpenAlexW4386221069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.