Evidence map›Paper›PMID 37763328›Full record

ArticleLife (Basel, Switzerland)2023

COVID-19 Vaccination and Serological Profile of a Brazilian University Population.

Marina Dos Santos Barreto, Beatriz Soares da Silva, Ronaldy Santana Santos, Deise Maria Rego Rodrigues Silva, Eloia Emanuelly Dias Silva, Pedro Henrique Macedo Moura, Jessiane Bispo de Souza, Lucas Alves da Mota Santana, Dennyson Leandro M Fonseca, Igor Salerno Filgueiras and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Marina Dos Santos BarretoDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.ORCID 0000-0003-4724-0688
Beatriz Soares da SilvaDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.
Ronaldy Santana SantosDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.ORCID 0000-0002-4928-7802
Deise Maria Rego Rodrigues SilvaDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.ORCID 0000-0001-8916-5271
Eloia Emanuelly Dias SilvaDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.ORCID 0000-0003-2895-4191
Pedro Henrique Macedo MouraDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.
Jessiane Bispo de SouzaDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.
Lucas Alves da Mota SantanaGraduate Program in Dentistry, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.
Dennyson Leandro M FonsecaInterunit Postgraduate Program on Bioinformatics, Institute of Mathematics and Statistics (IME), University of São Paulo (USP), São Paulo 05508-090, SP, Brazil.
Igor Salerno FilgueirasDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-3493-4464
Adriana Gibara GuimarãesDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.
Otavio Cabral-MarquesInterunit Postgraduate Program on Bioinformatics, Institute of Mathematics and Statistics (IME), University of São Paulo (USP), São Paulo 05508-090, SP, Brazil.ORCID 0000-0002-3183-6236
Lena F SchimkeDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-5616-3410
Lysandro Pinto BorgesDepartment of Pharmacy, Federal University of Sergipe, São Cristóvão 49100-000, SE, Brazil.ORCID 0000-0002-1721-1547
Universidade Federal de Sergipe · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 led to the suspension academic activities worldwide, affecting millions of students and staff.

methodsIn this study, we evaluated the presence of IgM and IgG anti-SARS-CoV-2 antibodies in an academic population during the return to classes after a one-year suspension. The study took place over five months at a Brazilian university and included 942 participants.

resultsWe found that most participants had reactive IgG and non-reactive IgM. All received at least one dose, and 940 received two or more doses, of different COVID-19 vaccines. We obtained a higher average of memory antibodies (IgG) in participants who received the CoronaVac/ChAdOx1 combination. IgG was consistently distributed for each vaccine group, but individuals who completed the vaccination schedule had higher levels. There were no differences between antibodies and gender, presence of symptoms, and previous COVID-19 infection, but older participants (>53 years) and contacts of infected individuals had higher IgM levels.

conclusionThis study makes significant contributions to the assessment of antibodies in the academic environment, allowing us to infer that most participants had memory immunity and low indications of recent infection when returning to face-to-face classes, as well as demonstrating the need to monitor immunity and update vaccinations.

Indexed as

academic populationantibodiesBrazilCOVID-19universitiesvaccines

Identifiers

PMID37763328
PMCPMC10532467
OpenAlexW4386814427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.