Evidence map›Paper›PMID 37763315›Full record

ArticleLife (Basel, Switzerland)2023

Epigenetic Aspects of a New Probiotic Concept-A Pilot Study.

Nina Okuka, Verena Schuh, Ulrike Krammer, Snezana Polovina, Mirjana Sumarac-Dumanovic, Neda Milinkovic, Ksenija Velickovic, Brizita Djordjevic, Alexander Haslberger, Nevena Dj Ivanovic

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Nina OkukaDepartment of Bromatology, Faculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.ORCID 0009-0004-5275-6667
Verena SchuhHealthBioCare GmbH, 1090 Vienna, Austria.
Ulrike KrammerHealthBioCare GmbH, 1090 Vienna, Austria.ORCID 0000-0001-6053-9604
Snezana PolovinaClinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-4838-689X
Mirjana Sumarac-DumanovicSchool of Medicine, University of Belgrade, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, 11000 Belgrade, Serbia.
Neda MilinkovicDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Ksenija VelickovicDepartment of Cell and Tissue Biology, Faculty of Biology, University of Belgrade; 11000 Belgrade, Serbia.
Brizita DjordjevicDepartment of Bromatology, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Alexander HaslbergerDepartment of Nutritional Science, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-9699-537X
Nevena Dj IvanovicDepartment of Bromatology, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-6620-5007
University of Belgrade · RSCenter for Health, Exercise and Sport Sciences · RSUniversity of Banja Luka · BAUniversity of Vienna · AT

Funding

Ministry of Education, Science, and Technological Development, the Republic of Serbia 451-03-02141/2017-09/35University of Belgrade 451-03-47/2023-01/ 200161
6 · The paper itself

Abstract

Several studies report the important role of an altered gut microbiota in the development of obesity, highlighting the potential use of probiotics in the treatment of obesity. The aim of this study is to investigate the effect of a novel probiotic approach on the expression of specific miRNAs and mRNAs associated with obesity in combination with the hypocholesterolemic octacosanol. Twenty overweight/obese women participated in a randomized, placebo-controlled, double-blind study and were randomly divided into two groups: the intervention group (daily one capsule containing

Indexed as

epigenetic markersLactobacillus plantarum 299vmiRNAsmRNAobesitypolicosanolsprobioticsSaccharomyces boulardii var. cerevisiaeSIRT1

Identifiers

PMID37763315
PMCPMC10533075
OpenAlexW4386780871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.