Evidence map›Paper›PMID 37763186›Full record

ArticleJournal of personalized medicine2023

Factors Affecting the Potential Efficacy of Intrauterine Platelet-Rich Plasma Infusion on Thin Endometrium in Women with Recurrent Implantation Failure.

Pin-Yao Lin, Chun-I Lee, Yi-Chun Chen, En-Hui Cheng, Chun-Chia Huang, Chung-I Chen, Tsung-Hsien Lee, Yu-Jen Lee, Maw-Sheng Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Advances in using biomaterials for repairing thin endometrium.Frontiers in bioengineering and biotechnology · 2025
    Review
  4. Regenerative therapies for refractory thin endometrium inFrontiers in cell and developmental biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pin-Yao LinInstitute of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Rd., South District, Taichung City 40201, Taiwan.ORCID 0000-0003-4602-5732
Chun-I LeeInstitute of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Rd., South District, Taichung City 40201, Taiwan.
Yi-Chun ChenDivision of Infertility, Lee Women's Hospital, No. 30-6, Sec. 1, Changping Road, Beitun District, Taichung City 406, Taiwan.
En-Hui ChengDivision of Infertility, Lee Women's Hospital, No. 30-6, Sec. 1, Changping Road, Beitun District, Taichung City 406, Taiwan.
Chun-Chia HuangDivision of Infertility, Lee Women's Hospital, No. 30-6, Sec. 1, Changping Road, Beitun District, Taichung City 406, Taiwan.
Chung-I ChenDivision of Infertility, Lee Women's Hospital, No. 30-6, Sec. 1, Changping Road, Beitun District, Taichung City 406, Taiwan.
Tsung-Hsien LeeInstitute of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Rd., South District, Taichung City 40201, Taiwan.ORCID 0000-0001-8858-0916
Yu-Jen LeeDivision of Infertility, Lee Women's Hospital, No. 30-6, Sec. 1, Changping Road, Beitun District, Taichung City 406, Taiwan.
Maw-Sheng LeeInstitute of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Rd., South District, Taichung City 40201, Taiwan.
Chung Shan Medical University Hospital · TWChung Shan Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimizing endometrial thickness (EMT) is crucial for successful embryo implantation, but enhancing thin endometrium remains a significant challenge. Platelet-rich plasma (PRP)-derived therapies have emerged as a promising approach in reproductive medicine due to their capacity to facilitate tissue repair and regeneration. This study aims to identify the risk factors associated with the failure of intrauterine PRP infusion for thin endometrium in women with recurrent implantation failure (RIF). We retrospectively reviewed data from 77 women with RIF, all exhibiting an EMT of <7 mm. These women underwent programmed hormone therapy for frozen embryo transfer (FET) and received two autologous intrauterine PRP infusions. Following intrauterine PRP-lysate (PL) infusions, the mean increase in EMT was 1.9 ± 1.2 mm, with EMT reaching 7 mm in 86% of the cases (66/77; average EMT, 8.3 mm). We identified an exceedingly thin EMT as a risk factor impacting the therapeutic efficacy in increasing EMT (

Indexed as

endometrial injuryendometrial receptivityfrozen embryo transferplatelet lysateplatelet-rich plasmarecurrent implantation failurethin endometrium

Identifiers

PMID37763186
PMCPMC10532920
OpenAlexW4386929430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.