Evidence map›Paper›PMID 37763157›Full record

ReviewJournal of personalized medicine2023

Revolutionizing Cancer Research: The Impact of Artificial Intelligence in Digital Biobanking.

Chiara Frascarelli, Giuseppina Bonizzi, Camilla Rosella Musico, Eltjona Mane, Cristina Cassi, Elena Guerini Rocco, Annarosa Farina, Aldo Scarpa, Rita Lawlor, Luca Reggiani Bonetti and 4 more

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Establishing a Cervical Cytology Biorepository: A Protocol for Advancing Translational Cervical Cancer Research through Biobanking.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
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  12. Deep learning algorithm on H&E whole slide images to characterizeComputational and structural biotechnology journal · 2024
    Article
  13. Closing Editorial: Colorectal Cancer-A Molecular Genetics Perspective.International journal of molecular sciences · 2024
    Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chiara FrascarelliDivision of Pathology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Giuseppina BonizziBiobank for Translational and Digital Medicine, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Camilla Rosella MusicoBiobank for Translational and Digital Medicine, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Eltjona ManeDivision of Pathology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Cristina CassiBiobank for Translational and Digital Medicine, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Elena Guerini RoccoDivision of Pathology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Annarosa FarinaCentral Information Systems and Technology Directorate, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.
Aldo ScarpaDepartment of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-1678-739X
Rita LawlorARC-Net Research Centre and Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Luca Reggiani BonettiSection of Pathology, Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, University Hospital of Modena, 41121 Modena, Italy.
Stefania CaramaschiSection of Pathology, Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, University Hospital of Modena, 41121 Modena, Italy.ORCID 0000-0003-2692-1281
Albino EccherSection of Pathology, Department of Medical and Surgical Sciences for Children and Adults, University of Modena and Reggio Emilia, University Hospital of Modena, 41121 Modena, Italy.ORCID 0000-0002-9992-5550
Stefano MarlettaDepartment of Diagnostics and Public Health, Section of Pathology, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-7881-8767
Nicola FuscoDivision of Pathology, IEO, European Institute of Oncology IRCCS, 20139 Milan, Italy.ORCID 0000-0002-9101-9131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBiobanks are vital research infrastructures aiming to collect, process, store, and distribute biological specimens along with associated data in an organized and governed manner. Exploiting diverse datasets produced by the biobanks and the downstream research from various sources and integrating bioinformatics and "omics" data has proven instrumental in advancing research such as cancer research. Biobanks offer different types of biological samples matched with rich datasets comprising clinicopathologic information. As digital pathology and artificial intelligence (AI) have entered the precision medicine arena, biobanks are progressively transitioning from mere biorepositories to integrated computational databanks. Consequently, the application of AI and machine learning on these biobank datasets holds huge potential to profoundly impact cancer research.

methodsIn this paper, we explore how AI and machine learning can respond to the digital evolution of biobanks with flexibility, solutions, and effective services. We look at the different data that ranges from specimen-related data, including digital images, patient health records and downstream genetic/genomic data and resulting "Big Data" and the analytic approaches used for analysis.

resultsThese cutting-edge technologies can address the challenges faced by translational and clinical research, enhancing their capabilities in data management, analysis, and interpretation. By leveraging AI, biobanks can unlock valuable insights from their vast repositories, enabling the identification of novel biomarkers, prediction of treatment responses, and ultimately facilitating the development of personalized cancer therapies.

conclusionsThe integration of biobanking with AI has the potential not only to expand the current understanding of cancer biology but also to pave the way for more precise, patient-centric healthcare strategies.

Indexed as

artificial intelligencebiobankcancer researchdigital pathology

Identifiers

PMID37763157
PMCPMC10532470

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.