Evidence map›Paper›PMID 37763132›Full record

ArticleJournal of personalized medicine2023

Molecular Profile of Variants in

Kaio Evandro Cardoso Aguiar, Izabela De Sousa Oliveira, Amanda De Nazaré Cohen-Paes, Rita De Cássia Calderaro Coelho, Lui Wallacy Morikawa Souza Vinagre, Juliana Carla Gomes Rodrigues, André Maurício Ribeiro-Dos-Santos, Sandro José De Souza, Ândrea Ribeiro-Dos-Santos, João Farias Guerreiro and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kaio Evandro Cardoso AguiarOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
Izabela De Sousa OliveiraOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.ORCID 0009-0005-8445-8119
Amanda De Nazaré Cohen-PaesOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.ORCID 0000-0003-3548-292X
Rita De Cássia Calderaro CoelhoOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
Lui Wallacy Morikawa Souza VinagreOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.ORCID 0000-0002-7063-6149
Juliana Carla Gomes RodriguesOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
André Maurício Ribeiro-Dos-SantosLaboratory of Human and Medical Genetics, Institute of Biological Science, Federal University of Pará, Belém 66077-830, PA, Brazil.
Sandro José De SouzaBrain Institute, Universidade Federal do Rio Grande do Norte, Natal 59078-970, RN, Brazil.
Ândrea Ribeiro-Dos-SantosLaboratory of Human and Medical Genetics, Institute of Biological Science, Federal University of Pará, Belém 66077-830, PA, Brazil.ORCID 0000-0001-7001-1483
João Farias GuerreiroOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.ORCID 0000-0003-1979-3656
Paulo Pimentel de AssumpçãoOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
Sidney Emanuel Batista Dos SantosOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
Ney Pereira Carneiro Dos SantosOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.
Marianne Rodrigues FernandesOncology Research Center, Federal University of Pará, Belém 66073-005, PA, Brazil.ORCID 0000-0002-1396-3442
Universidade Federal do Pará · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric Cancer is a disease associated with environmental and genetic changes, becoming one of the most prevalent cancers around the world and with a high incidence in Brazil. However, despite being a highly studied neoplastic type, few efforts are aimed at populations with a unique background and genetic profile, such as the indigenous peoples of the Brazilian Amazon. Our study characterized the molecular profile of five genes associated with the risk of developing gastric cancer by sequencing the complete exome of 64 indigenous individuals belonging to 12 different indigenous populations in the Amazon. The analysis of the five genes found a total of 207 variants, of which 15 are new in our indigenous population, and among these are two with predicted high impact, present in the

Indexed as

exomegastric cancergenomicsindigenous population

Identifiers

PMID37763132
PMCPMC10532670
OpenAlexW4386547021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.