ArticleJournal of personalized medicine2023
The Relationship of Cognitive Dysfunction with Inflammatory Markers and Carotid Intima Media Thickness in Schizophrenia.
Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Serum IL-17A and CCL20 levels and their correlation with obsessive-compulsive disorder and suicidality in schizophrenia and bipolar mood disorder.BMC psychiatry · 2026Article
- The interplay of niacin skin flush response with plasma MDA, TNOS, iNOS and clinical symptom severity in chronic schizophrenia.BMC psychiatry · 2026Article
- The relationship between cognitive function and inflammatory-nutritional status in schizophrenia: cognitive impairment is inversely related to PNI and CALLY indices.BMC psychiatry · 2026Article
- Integrative multi-omics profiling of mild cognitive impairment in older patients combined with coronary heart disease: a cross-sectional cohort study.Frontiers in cardiovascular medicine · 2026Article
- The impact of cardiometabolic multimorbidity on cognitive function in older adults: a review.Frontiers in public health · 2026Review
- Vitamin D, systemic inflammation, and motoric cognitive risk: exploring the risk factors and mediation pathways.Frontiers in aging · 2026Article
- Reduced Neutrophil-to-Eosinophil Ratio in Chronic Dacryocystitis: A Hematological Clue to Allergic Pathogenesis.Journal of ophthalmology · 2026Article
- Clozapine-Induced Gastrointestinal Hypoperfusion Leading to Bowel Ischemia and Secondary Atrial Fibrillation: A Case Report.Case reports in psychiatry · 2026Article
- Interaction between serum inflammatory cytokines and brain-derived neurotrophic factor in cognitive function among first-episode schizophrenia patients.World journal of psychiatry · 2024Article
- Multimorbidity in Severe Mental Illness as Part of the Neurodevelopmental Continuum: Physical Health-Related Endophenotypes of Schizophrenia-A Narrative Review.Brain sciences · 2024Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSchizophrenia is a devastating and chronic mental disorder that affects 1% of the population worldwide. It is also associated with cognitive dysfunction and cardiovascular risk factors. The aim of this study is to investigate the relationship between cognitive impairment and some inflammatory markers and carotid intima-media thickness (CIMT) in schizophrenia.
methodsThe participants of this study were 51 schizophrenia and 57 healthy controls (HC). The Positive and Negative Syndrome Scale (PANSS) was used for severity of illness, and the Montreal Cognitive Assessment Scale (MoCA) was used for cognitive functioning. The MoCA scores, some biochemical and inflammatory markers, and CIMT were compared between schizophrenia and HC groups.
resultsOf the patients with schizophrenia, 11 were women (21.6%), and 40 were men (78.4%). MoCA scores were lower, and levels of NLR, MLR, PLR, SII, CRP, ESR, and CIMT were higher in schizophrenia compared to the HC group (respectively;
conclusionsThis is the first study to show the relationship between cognitive impairment and CIMT in schizophrenia. In this study, NLR, MLR, PLR, SII, CRP, and ESR markers were higher in schizophrenia compared to HC, indicating inflammation. Our finding of elevated CIMT in schizophrenia suggests that there may be an atherosclerotic process along with the inflammatory process. The finding of a positive correlation between cognitive impairment and CIMT may be promising for new therapies targeting the atherosclerotic process in the treatment of cognitive impairment.
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