Evidence map›Paper›PMID 37763101›Full record

ArticleJournal of personalized medicine2023

SARS-CoV-2 Infection, Vaccination and Risk of Death in People with An Oncological Disease in Northeast Italy.

Lucia Mangone, Paolo Giorgi Rossi, Martina Taborelli, Federica Toffolutti, Pamela Mancuso, Luigino Dal Maso, Michele Gobbato, Elena Clagnan, Stefania Del Zotto, Marta Ottone and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lucia MangoneEpidemiology Unit, AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.ORCID 0000-0002-5089-5178
Paolo Giorgi RossiEpidemiology Unit, AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Martina TaborelliUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.ORCID 0000-0002-6731-7569
Federica ToffoluttiUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.
Pamela MancusoEpidemiology Unit, AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.ORCID 0000-0003-1609-2440
Luigino Dal MasoUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.ORCID 0000-0001-6163-200X
Michele GobbatoAgenzia Regionale di Coordinamento per la Salute Udine, 33100 Udine, Italy.
Elena ClagnanAgenzia Regionale di Coordinamento per la Salute Udine, 33100 Udine, Italy.ORCID 0000-0002-7756-2226
Stefania Del ZottoAgenzia Regionale di Coordinamento per la Salute Udine, 33100 Udine, Italy.
Marta OttoneEpidemiology Unit, AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.ORCID 0000-0003-1302-0329
Isabella BiscegliaEpidemiology Unit, AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.ORCID 0000-0002-9225-781X
Antonino NeriScientific Directorate, AUSL-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Diego SerrainoUnit of Cancer Epidemiology, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.ORCID 0000-0003-0565-8920
Azienda Sanitaria Unità Locale di Reggio Emilia · ITCentro di Riferimento Oncologico · IT

Funding

Ministero della Salute Ricerca Corrente 2023
6 · The paper itself

Abstract

People with a history of cancer have a higher risk of death when infected with SARS-CoV-2. COVID-19 vaccines in cancer patients proved safe and effective, even if efficacy may be lower than in the general population. In this population-based study, we compare the risk of dying of cancer patients diagnosed with COVID-19 in 2021, vaccinated or non-vaccinated against SARS-CoV-2 and residing in Friuli Venezia Giulia or in the province of Reggio Emilia. An amount of 800 deaths occurred among 6583 patients; the risk of death was more than three times higher among unvaccinated compared to vaccinated ones [HR 3.4; 95% CI 2.9-4.1]. The excess risk of death was stronger in those aged 70-79 years [HR 4.6; 95% CI 3.2-6.8], in patients with diagnosis made <1 year [HR 8.5; 95% CI 7.3-10.5] and in all cancer sites, including hematological malignancies. The study results indicate that vaccination against SARS-CoV-2 infection is a necessary tool to be included in the complex of oncological therapies aimed at reducing the risk of death.

Indexed as

COVID-19risk of deathtumorsvaccination

Identifiers

PMID37763101
PMCPMC10532764
OpenAlexW4386286157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.