ArticleJournal of clinical medicine2023
Umbilical Granuloma: Frequency, Associated Factors, 10-Year Treatment Trends, and Effectiveness at a Single Hospital in Japan.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- What should be investigated in delayed umbilical cord separation: Two case reports.World journal of clinical pediatrics · 2025Article
- Cord care practices and related outcomes among caregivers in two referral facilities in Ghana: a cross-sectional study.BMC pediatrics · 2025Article
- Coexisting Remnants of the Omphalomesenteric Duct and Urachus in an Infant.Surgical case reports · 2025Article
- Prolapsed Umbilical Meckel's Diverticulum Mimicking Umbilical Granuloma: A Rare Differential of a Common Problem.Cureus · 2024Article
- Chemical Burns Caused by Topical Silver Nitrate in Umbilical Granuloma Treatment: A Case Report.Cureus · 2024Article
- Efficacy and Safety of Common Salt and other Topical Agents in the Treatment of Umbilical Granuloma in Neonates and Infants: A Systematic Review and Meta-analysis.Journal of Indian Association of Pediatric SurgeonsReview
- A Study of Symptomatic Umbilical Remnants in Children with Evaluation of the Role of Ultrasound as a Diagnostic Modality.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Umbilical granuloma (UG) is a common problem during the neonatal period; however, its epidemiology and etiology are poorly studied, and the best treatment option has not yet been established. We examined the medical records of neonates who were born and underwent 1-month evaluations at our hospital between 2013 and 2022 to investigate the frequency of-and factors associated with-UG, as well as the annual trends of UG treatments and their efficacy. Of the 6680 eligible neonates, 395 (5.9%) had UG. The annual incidence rate ranged from 3.8% to 7.3%. Gestational age, birth weight, and incidence of meconium-stained amniotic fluid were significantly associated with UG. Silver nitrate cauterization was the predominant UG treatment from 2013 to 2016. Silver nitrate cauterization and topical betamethasone valerate were nearly equally applied in 2017. Betamethasone application became predominant in 2018. The healing rates during the initial treatment period were 91% for silver nitrate cauterization, 97.7% for betamethasone application, 60% for ethanol disinfection, and 88% for ligation; these rates were significantly different (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.