Evidence map›Paper›PMID 37762995›Full record

ReviewJournal of clinical medicine2023

Transcatheter Aortic Valve Implantation and Cardiac Conduction Abnormalities: Prevalence, Risk Factors and Management.

Michał Szotek, Łukasz Drużbicki, Karol Sabatowski, Gisella R Amoroso, Koen De Schouwer, Paweł T Matusik

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07343674 recruitingnot on this mapstarted 2026, after this paper: background citation

PERFECT - Portuguese Evolut Registry Studying the Outcomes of Medtronic Evolut™ FX+ TAVI System by Evaluating an Optimal Care Pathway for TAVI

Typeobservational_patient_registrySponsorPortuguese Association of Interventional CardiologyRan2026 to 2028Enrolled500ConditionsSevere Symptomatic Aortic Stenosis (Defined as New York Heart Association (NYHA) Class ≥ II)
NCT07456280 narecruitingnot on this mapstarted 2026, after this paper: background citation

Pilot Study to Evaluate a Noninvasive Electrocardiographic Monitoring Strategy Associated With Early Discharge in Patients With Conduction Disorders Following TAVI Implantation (IMPROVE Study)

TypeinterventionalSponsorHospital Universitari Vall d'Hebron Research InstituteRan2026 to 2028Enrolled100ConditionsSevere Aortic Valve Stenosis, Cardiovascular DiseasesArmsStandard care, PhysioMem PM 100 4G ambulatory monitoring system
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Michał SzotekDepartment of Electrocardiology, The John Paul II Hospital, 80 Prądnicka St., 31-202 Kraków, Poland.
Łukasz DrużbickiDepartment of Cardiovascular Surgery and Transplantology, The John Paul II Hospital, 80 Prądnicka St., 31-202 Kraków, Poland.
Karol SabatowskiDepartment of Cardiology and Cardiovascular Interventions, University Hospital, 2 Jakubowskiego St., 30-688 Kraków, Poland.
Gisella R AmorosoDepartment of Cardiovascular Medicine, "SS Annunziata" Hospital, ASL CN1-Savigliano, Via Ospedali 9, 12038 Savigliano, Italy.
Koen De SchouwerDepartment of Cardiology, Cardiovascular Center, Onze-Lieve-Vrouwziekenhuis Hospital, Moorselbaan 164, 9300 Aalst, Belgium.ORCID 0000-0001-6537-7085
Paweł T MatusikDepartment of Electrocardiology, The John Paul II Hospital, 80 Prądnicka St., 31-202 Kraków, Poland.ORCID 0000-0001-5788-575X
John Paul II Hospital · PLJagiellonian University · PLOnze Lieve Vrouwziekenhuis Hospital · BEOspedale SS. Annunziata · IT

Funding

Jagiellonian University Medical College N41/DBS/000845Ministry of Science and Higher Education Stipend for outstanding young scientistsNational Science Centre 2021/05/X/NZ5/01511the John Paul II Hospital NA
6 · The paper itself

Abstract

Over the last decades, transcatheter aortic valve implantation (TAVI) or replacement (TAVR) has become a potential, widely accepted, and effective method of treating aortic stenosis in patients at moderate and high surgical risk and those disqualified from surgery. The method evolved what translates into a noticeable decrease in the incidence of complications and more beneficial clinical outcomes. However, the incidence of conduction abnormalities related to TAVI, including left bundle branch block and complete or second-degree atrioventricular block (AVB), remains high. The occurrence of AVB requiring permanent pacemaker implantation is associated with a worse prognosis in this group of patients. The identification of risk factors for conduction disturbances requiring pacemaker placement and the assessment of their relation to pacing dependence may help to develop methods of optimal care, including preventive measures, for patients undergoing TAVI. This approach is crucial given the emerging evidence of no worse outcomes for intermediate and low-risk patients undergoing TAVI in comparison to surgical aortic valve replacement. This paper comprehensively discusses the mechanisms, risk factors, and consequences of conduction abnormalities and arrhythmias, including AVB, atrial fibrillation, and ventricular arrhythmias associated with aortic stenosis and TAVI, as well as provides insights into optimized patient care, along with the potential of conduction system pacing and cardiac resynchronization therapy, to minimize the risk of unfavorable clinical outcomes.

Indexed as

arrhythmiaatrioventricular blockcardiovascular implantable electronic devicesconduction abnormalitiesleft bundle branch blockpacemaker implantationTAVRtranscatheter aortic valve implantation

Identifiers

PMID37762995
PMCPMC10531796
OpenAlexW4386895262

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.