Evidence map›Paper›PMID 37762794›Full record

ArticleJournal of clinical medicine2023

Targeted Radiation Exposure Induces Accelerated Aortic Valve Remodeling in ApoE

Guillaume Rucher, Kevin Prigent, Christophe Simard, Anne-Marie Frelin, Maëlle Coquemont-Guyot, Nicolas Elie, Nicolas Delcroix, Nicolas Perzo, Romain Guinamard, Ludovic Berger and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Guillaume RucherNormandie Univ, UNICAEN, UR 4650 PSIR, GIP Cyceron, 14000 Caen, France.
Kevin PrigentNormandie Univ, UNICAEN, UR 4650 PSIR, GIP Cyceron, 14000 Caen, France.ORCID 0000-0003-3234-5284
Christophe SimardNormandie Univ, UNICAEN, UR 4650 PSIR, GIP Cyceron, 14000 Caen, France.
Anne-Marie FrelinGrand Accélérateur National d'Ions Lourds (GANIL), CEA/DRF-CNRS/IN2P3, 14000 Caen, France.ORCID 0000-0002-0545-8577
Maëlle Coquemont-GuyotNormandie Univ, UNICAEN, SF 4207, PLATON Services Unit, Virtual'His, 14000 Caen, France.
Nicolas ElieNormandie Univ, UNICAEN, SF 4207, PLATON Services Unit, Virtual'His, 14000 Caen, France.ORCID 0000-0001-5772-8252
Nicolas DelcroixCNRS, UMS-3048, GIP Cyceron, Campus Jules Horowitz, 14000 Caen, France.
Nicolas PerzoNormandie Univ, UNIROUEN, INSERM U1096 EnVI, 76000 Rouen, France.ORCID 0000-0002-0854-1931
Romain GuinamardNormandie Univ, UNICAEN, UR 4650 PSIR, GIP Cyceron, 14000 Caen, France.
Ludovic BergerNormandie Univ, UNICAEN, UR 4650 PSIR, GIP Cyceron, 14000 Caen, France.
Alain ManriqueNormandie Univ, UNICAEN, UR 4650 PSIR, GIP Cyceron, 14000 Caen, France.ORCID 0000-0002-1578-0922
On Behalf Of The Stop-As Investigators
Normandie Université · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

Agence Nationale de la Recherche ANR-16-RHUS-0003
6 · The paper itself

Abstract

Thoracic radiation therapy may result in accelerated atherosclerosis and in late aortic valve stenosis (AS). In this study, we assessed the feasibility of inducing radiation-induced AS using a targeted aortic valve irradiation (10 or 20 Grays) in two groups of C57Bl6/J (WT) and ApoE

Indexed as

aortic stenosismagnetic resonance imagingmineralizationradiation therapy

Identifiers

PMID37762794
PMCPMC10531867
OpenAlexW4386614812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.