ReviewJournal of clinical medicine2023
Surgical Treatment of Spheno-Orbital Meningiomas: A Systematic Review and Meta-Analysis of Surgical Techniques and Outcomes.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- State of the art and future perspectives on the management of spheno-orbital meningiomas: a meta-analysis comparing transorbital and transcranial approaches.Frontiers in oncology · 2026Pooled it
- Association of hormone therapy with spheno-orbital meningiomas: bridging evidence and unknowns.Frontiers in oncology · 2026Pooled it
- Microsurgical Treatment of Spheno-Orbital Meningiomas: The Clinical Significance of the Tumor Invasion into the Greater Sphenoid Wing.Journal of neurological surgery. Part B, Skull base · 2026Article
- Sphenoid Temporal Meningioma With Granular Cell Features and Extracranial Infratemporal Extension.Cureus · 2026Article
- Minimally invasive resection of a spheno-orbital tumor: Review of surgical techniques and a case report.Surgical neurology international · 2026Article
- Transorbital approach: a bibliometric analysis from 1948 to 2024.Acta neurochirurgica · 2025Review
- Transorbital management of selected spheno-orbital meningiomas: Insights from a multicentric retrospective Italian study of 52 cases.Neurosurgical review · 2025Article
- Endoscopic Transorbital Approach and Transcranial Approach in Spheno-Orbital Meningiomas: A Comparative Qualitative and Preliminary Quantitative Anatomical Study.Journal of clinical medicine · 2025Article
- Location-specific outcomes and complications of endoscopic transorbital approaches: A systematic review with novel anatomical grouping.Brain & spine · 2025Article
- Surgical management and postoperative outcomes of orbital cavernous malformations: A systematic literature review by the EANS skull base section.Brain & spine · 2025Review
- Advantages and limitations of orbital rim resection in transorbital endoscopic approach: an anatomical study.Acta neurochirurgica · 2024Article
- Single-step 3D printing aided cranio-orbital reconstruction with patient specific polyetheretherketone implants after resection of benign spheno-orbital tumors.Acta neurochirurgica · 2024Article
- Endoscopic transorbital approach for recurrent spheno-orbital meningiomas: single center case series.Neurosurgical review · 2024Article
- Spheno-Orbital Meningiomas: The Rationale behind the Decision-Making Process of Treatment Strategy.Cancers · 2024Article
- The Transorbital Approach: A Comprehensive Review of Targets, Surgical Techniques, and Multiportal Variants.Journal of clinical medicine · 2024Review
- Correlation Analysis on Anatomical Variants of Accessory Foramina in the Sphenoid Bone for Oncological Surgery.Cancers · 2023Article
- The Transorbital Approach, A Game-Changer in Neurosurgery: A Guide to Safe and Reliable Surgery Based on Anatomical Principles.Journal of clinical medicine · 2023Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpheno-orbital meningiomas (SOMs) are rare tumors arising from the meninges surrounding the sphenoid bone and orbital structures. Surgical resection is the primary treatment approach for SOMs. Several surgical approaches have been described during the decades, including microsurgical transcranial (MTAs), endoscopic endonasal (EEAs), endoscopic transorbital (ETOAs), and combined approaches, and the choice of surgical approach remains a topic of debate. PURPOSE: This systematic review and meta-analysis aim to compare the clinical and surgical outcomes of different surgical approaches used for the treatment of SOMs, discussing surgical techniques, outcomes, and factors influencing surgical decision making.
methodsA comprehensive literature review of the databases PubMed, Ovid MEDLINE, and Ovid EMBASE was conducted for articles published on the role of surgery for the treatment of SOMs until 2023. The systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Meta-analysis was performed to estimate pooled event rates and assess heterogeneity. Fixed- and random-effects were used to assess 95% confidential intervals (CIs) of presenting symptoms, outcomes, and complications.
resultsA total of 59 studies comprising 1903 patients were included in the systematic review and meta-analysis. Gross total resection (GTR) rates ranged from 23.5% for ETOAs to 59.8% for MTAs. Overall recurrence rate after surgery was 20.7%. Progression-free survival (PFS) rates at 5 and 10 years were 75.5% and 49.1%, respectively. Visual acuity and proptosis improvement rates were 57.5% and 79.3%, respectively. Postoperative cranial nerve (CN) focal deficits were observed in 20.6% of cases. The overall cerebro-spinal fluid (CSF) leak rate was 3.9%, and other complications occurred in 13.9% of cases. MTAs showed the highest GTR rates (59.8%, 95%CI = 49.5-70.2%;
conclusionSurgical treatment of SOMs aims to preserve visual function and improve proptosis. Different surgical approaches offer varying rates of GTR, complications, and functional outcomes. A multidisciplinary approach involving a skull base team is crucial for optimizing patient outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.