Evidence map›Paper›PMID 37762758›Full record

ReviewJournal of clinical medicine2023

Diagnostic Work-Up in Patients with Nonbacterial Thrombotic Endocarditis.

Antonio Tonutti, Iside Scarfò, Giovanni La Canna, Carlo Selmi, Maria De Santis

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. A rare presentation of nonbacterial thrombotic endocarditis.Journal of vascular surgery cases and innovative techniques · 2026
    Article
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  10. Review
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  17. Diagnostics (Basel, Switzerland) · 2025
    Review
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Antonio TonuttiDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy.ORCID 0009-0000-9534-6853
Iside ScarfòApplied Diagnostic Echocardiography Unit, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
Giovanni La CannaApplied Diagnostic Echocardiography Unit, IRCCS Humanitas Research Hospital, 20089 Rozzano, Italy.
Carlo SelmiDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy.ORCID 0000-0002-0323-0376
Maria De SantisDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, Italy.ORCID 0000-0002-3196-1336
Humanitas University · ITIRCCS Humanitas Research Hospital · IT

Funding

This work was partially supported by "Ricerca Corrente" funding from Italian Ministry of Health to IRCCS Humanitas Research Hospital Ricerca Corrente
6 · The paper itself

Abstract

Nonbacterial thrombotic endocarditis (NBTE) is a form of endocarditis that occurs in patients with predisposing conditions, including malignancies, autoimmune diseases (particularly antiphospholipid antibody syndrome, which accounts for the majority of lupus-associated cases), and coagulation disturbances for which the correlation with classical determinants is unclear. The condition is commonly referred to as "marantic", "verrucous", or Libman-Sacks endocarditis, although these are not synonymous, representing clinical-pathological nuances. The clinical presentation of NBTE involves embolic events, while local valvular complications, generally regurgitation, are typically less frequent and milder compared to infective forms of endocarditis. In the past, the diagnosis of NBTE relied on post mortem examinations, while at present, the diagnosis is primarily based on echocardiography, with the priority of excluding infective endocarditis through comprehensive microbiological and serological tests. As in other forms of endocarditis, besides pathology, transesophageal echocardiography remains the diagnostic standard, while other imaging techniques hold promise as adjunctive tools for early diagnosis and differentiation from infective vegetations. These include cardiac MRI and

Indexed as

anticoagulantsantiphospholipid antibodiescardiac imagingcoagulopathyechocardiographyimmunologyLibman–Sacksmaranticnon-infective endocarditis

Identifiers

PMID37762758
PMCPMC10532023
OpenAlexW4386496049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.