Evidence map›Paper›PMID 37762625›Full record

Trial reportInternational journal of molecular sciences2023

Treatment with the Topical Antimicrobial Peptide Omiganan in Mild-to-Moderate Facial Seborrheic Dermatitis versus Ketoconazole and Placebo: Results of a Randomized Controlled Proof-of-Concept Trial.

Jannik Rousel, Mahdi Saghari, Lisa Pagan, Andreea Nădăban, Tom Gambrah, Bart Theelen, Marieke L de Kam, Jorine Haakman, Hein E C van der Wall, Gary L Feiss and 5 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Emerging antimicrobial peptides in gastrointestinal disorders: Dual role in immunity and therapy.World journal of gastrointestinal pharmacology and therapeutics · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Candida albicans and Antifungal Peptides.Infectious diseases and therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Jannik RouselCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.ORCID 0000-0003-0986-3753
Mahdi SaghariCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.ORCID 0000-0002-3829-0037
Lisa PaganCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.ORCID 0000-0002-2064-7501
Andreea NădăbanLeiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.ORCID 0000-0002-4981-6268
Tom GambrahCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.
Bart TheelenWesterdijk Fungal Biodiversity Institute, 3508 AD Utrecht, The Netherlands.ORCID 0000-0003-1333-2058
Marieke L de KamCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.
Jorine HaakmanCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.ORCID 0009-0003-3142-7066
Hein E C van der WallCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.ORCID 0000-0002-7437-7746
Gary L FeissCutanea Life Sciences, Wayne, PA 19087, USA.
Tessa Niemeyer-van der KolkCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.
Jacobus BurggraafCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.ORCID 0000-0001-7912-0918
Joke A BouwstraLeiden Academic Centre for Drug Research, Leiden University, 2333 CC Leiden, The Netherlands.
Robert RissmannCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.
Martijn B A van DoornCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.
Centre for Human Drug Research · NLLeiden University · NLLeiden University Medical Center · NLWesterdijk Fungal Biodiversity Institute · NL

Funding

Cutanea Life Sciences, Wayne, Pennsylvania, USA n.a.Maruho Co. Ltd., Kyoto, Japan n.a.
6 · The paper itself

Abstract

Facial seborrheic dermatitis (SD) is an inflammatory skin disease characterized by erythematous and scaly lesions on the skin with high sebaceous gland activity. The yeast

Indexed as

Dermatitis, SeborrheicMalasseziaAntifungal AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesHumansKetoconazoleTreatment OutcomeAntifungal AgentsAntimicrobial Cationic PeptidesAntimicrobial PeptidesKetoconazoleOmigananketoconazoleMalasseziamultimodalomigananseborrheic dermatitisskin barrierStaphylococcus

Identifiers

PMID37762625
PMCPMC10531869
OpenAlexW4386879574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.