ReviewInternational journal of molecular sciences2023
The Mechanisms and Efficacy of Photobiomodulation Therapy for Arthritis: A Comprehensive Review.
Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Photobiomodulation in carpal tunnel syndrome with pain, strength, and functionality analysis: a systematic review and meta-analysis.Lasers in medical science · 2025Pooled it
- Trial
- Low-power infrared laser on telomere maintenance in an experimental model of arthritis.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- Comparison Between Ultrasonic and Thermal Exfoliation for Molybdenum Disulfide Nanoparticles-A Multifunctional Study.Nanomaterials (Basel, Switzerland) · 2026Article
- Endoanal ultrasound-measured internal anal sphincter changes after nonablative 1470-nm diode laser therapy for anal incontinence: a prospective single-arm pilot study.Techniques in coloproctology · 2026Article
- Mapping the Translational Research Structure of Photobiomodulation in Osteoarthritis: A Bibliometric Analysis.Bioengineering (Basel, Switzerland) · 2026Review
- Photobiomodulation for skeletal muscle regeneration: mechanisms, dosimetry, and translational challenges.Frontiers in bioengineering and biotechnology · 2026Review
- Nanomaterial-Based Photothermal Therapy for Inflammatory Diseases: Intervention Strategies, Synergistic Effects, and Future Challenges.International journal of nanomedicine · 2026Review
- A novel method for establishing a rat model of knee osteoarthritis: knee joint fixation using medical polyurethane composite wraps.Frontiers in veterinary science · 2026Article
- From light to healing: photobiomodulation therapy in medical disciplines.Journal of translational medicine · 2025Review
- Photobiomodulation limits oral ulcer development by regulating the immune response.BMC oral health · 2025Article
- Feasibility of Multimodal Energy-Based Therapy for Pelvic Floor Disorders.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Modulating macrophage polarization by photobiomodulation.Lasers in medical science · 2025Review
- Effects of 650 nm laser acupuncture on cartilage, bone, and skeletal muscle in osteoarthritis.Bone reports · 2025Article
- Perovskites to Photonics: Engineering NIR LEDs for Photobiomodulation.Micromachines · 2025Article
- Local oxygen concentration reversal from hyperoxia to hypoxia monitored by optical-resolution photoacoustic microscopy in inflammation-resolution process.Photoacoustics · 2025Article
- Photobiomodulation in Promoting Cartilage Regeneration.International journal of molecular sciences · 2025Review
- Illuminating eye care: the promise and future of red light therapy in ophthalmology.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- MiR-451 in Inflammatory Diseases: Molecular Mechanisms, Biomarkers, and Therapeutic Applications-A Comprehensive Review Beyond Oncology.Current issues in molecular biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Rheumatoid arthritis (RA) and osteoarthritis (OA) have a significant impact on the quality of life of patients around the world, causing significant pain and disability. Furthermore, the drugs used to treat these conditions frequently have side effects that add to the patient's burden. Photobiomodulation (PBM) has emerged as a promising treatment approach in recent years. PBM effectively reduces inflammation by utilizing near-infrared light emitted by lasers or LEDs. In contrast to photothermal effects, PBM causes a photobiological response in cells, which regulates their functional response to light and reduces inflammation. PBM's anti-inflammatory properties and beneficial effects in arthritis treatment have been reported in numerous studies, including animal experiments and clinical trials. PBM's effectiveness in arthritis treatment has been extensively researched in arthritis-specific cells. Despite the positive results of PBM treatment, questions about specific parameters such as wavelength, dose, power density, irradiation time, and treatment site remain. The goal of this comprehensive review is to systematically summarize the mechanisms of PBM in arthritis treatment, the development of animal arthritis models, and the anti-inflammatory and joint function recovery effects seen in these models. The review also goes over the evaluation methods used in clinical trials. Overall, this review provides valuable insights for researchers investigating PBM treatment for arthritis, providing important references for parameters, model techniques, and evaluation methods in future studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.