Evidence map›Paper›PMID 37762570›Full record

ReviewInternational journal of molecular sciences2023

The Essential Role of PCR and PCR Panel Size in Comparison with Urine Culture in Identification of Polymicrobial and Fastidious Organisms in Patients with Complicated Urinary Tract Infections.

Xingpei Hao, Marcus Cognetti, Chiraag Patel, Nathalie Jean-Charles, Arun Tumati, Rhonda Burch-Smith, Mara Holton, Deepak A Kapoor

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xingpei HaoP4 Diagnostix, Pine Brook, NJ 07058, USA.
Marcus CognettiP4 Diagnostix, Pine Brook, NJ 07058, USA.
Chiraag PatelP4 Diagnostix, Pine Brook, NJ 07058, USA.
Nathalie Jean-CharlesP4 Diagnostix, Pine Brook, NJ 07058, USA.
Arun TumatiP4 Diagnostix, Pine Brook, NJ 07058, USA.
Rhonda Burch-SmithP4 Diagnostix, Pine Brook, NJ 07058, USA.
Mara HoltonAnne Arundel Urology, Annapolis, MD 21401, USA.
Deepak A KapoorSolaris Health Holdings, LLC, Fort Lauderdale, FL 33394, USA.ORCID 0000-0001-9727-1752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complicated urinary tract infections (cUTIs) are difficult to treat, consume substantial resources, and cause increased patient morbidity. Data suggest that cUTI may be caused by polymicrobial and fastidious organisms (PMOs and FOs, respectively); as such, urine culture (UC) may be an unreliable diagnostic tool for detecting cUTIs. We sought to determine the utility of PCR testing for patients presumed to have a cUTI and determine the impact of PCR panel size on organism detection. We reviewed 36,586 specimens from patients with presumptive cUTIs who received both UC and PCR testing. Overall positivity rate for PCR and UC was 52.3% and 33.9%, respectively (

Indexed as

Urinary Tract InfectionsAnti-Bacterial AgentsHumansPolymerase Chain ReactionUrinalysisAnti-Bacterial Agentscomplicated urinary tract infectionfastidious organismmolecular testingPCRpolymicrobial organismurine culture

Identifiers

PMID37762570
PMCPMC10531650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.