Evidence map›Paper›PMID 37762548›Full record

ArticleInternational journal of molecular sciences2023

Isolinderalactone Induces Apoptosis, Autophagy, Cell Cycle Arrest and MAPK Activation through ROS-Mediated Signaling in Colorectal Cancer Cell Lines.

Jith-Shyan Chen, Sheng-Chun Chiu, Sung-Ying Huang, Shu-Fang Chang, Kuan-Fu Liao

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  3. Sleep disorders in hepatocellular carcinoma.World journal of gastrointestinal oncology · 2025
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  8. Effect ofNutrients · 2024
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jith-Shyan ChenDepartment of Obstetrics and Gynecology, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.
Sheng-Chun ChiuDepartment of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.ORCID 0000-0002-5927-8088
Sung-Ying HuangDepartment of Ophthalmology, Hsinchu Mackay Memorial Hospital, Hsinchu 300044, Taiwan.
Shu-Fang ChangDepartment of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.
Kuan-Fu LiaoDepartment of Internal Medicine, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.
Taipei Tzu Chi Hospital · TWMackay Memorial Hospital · TWTzu Chi University · TW

Funding

Buddhist Tzu Chi Medical Foundation TCMF-A 108-014Buddhist Tzu Chi Medical Foundation TTCRD110-21Buddhist Tzu Chi Medical Foundation TTCRD110-31Buddhist Tzu Chi Medical Foundation TTCRD111-33
6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Isolinderalactone (ILL), a sesquiterpene isolated from the root extract of

Indexed as

Colorectal NeoplasmsSesquiterpenesApoptosisAutophagyCell Cycle CheckpointsCell Line, TumorCell ProliferationG2 Phase Cell Cycle CheckpointsHumansReactive Oxygen SpecieslinderalactoneReactive Oxygen SpeciesSesquiterpenesapoptosisautophagycolorectal cancerG2/M arrestisolinderalactoneROS

Identifiers

PMID37762548
PMCPMC10532319
OpenAlexW4386934729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.