Evidence map›Paper›PMID 37762457›Full record

ArticleInternational journal of molecular sciences2023

Early Alzheimer's Disease Screening Approach Using Plasma Biomarkers.

Lourdes Álvarez-Sánchez, Carmen Peña-Bautista, Laura Ferré-González, Laura Cubas, Angel Balaguer, Bonaventura Casanova-Estruch, Miguel Baquero, Consuelo Cháfer-Pericás

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Reframing TDP-43 in Alzheimer's disease: From co-pathology to neurovascular culprit.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lourdes Álvarez-SánchezAlzheimer Disease Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0002-7016-9739
Carmen Peña-BautistaAlzheimer Disease Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.
Laura Ferré-GonzálezAlzheimer Disease Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0003-4631-4761
Laura CubasDivision of Neuroinmunology, University and Polytechnic Hospital La Fe, 46026 Valencia, Spain.
Angel BalaguerMath Faculty, Universitat de València, 46026 Valencia, Spain.
Bonaventura Casanova-EstruchDivision of Neuroinmunology, University and Polytechnic Hospital La Fe, 46026 Valencia, Spain.
Miguel BaqueroAlzheimer Disease Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.
Consuelo Cháfer-PericásAlzheimer Disease Research Group, Health Research Institute La Fe, 46026 Valencia, Spain.ORCID 0000-0002-0711-5877
Leitat Technological Center · ESHospital Universitari i Politècnic La Fe · ESUniversitat de València · ES

Funding

Instituto de salud carlos iii PI22/00594
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most prevalent dementia, but it shows similar initial symptoms to other neurocognitive diseases (Lewy body disease (LBD) and frontotemporal dementia (FTD)). Thus, the identification of reliable AD plasma biomarkers is required. The aim of this work is to evaluate the use of a few plasma biomarkers to develop an early and specific AD screening method. Plasma p-Tau181, neurofilament light (NfL), and glial fibrillary acid protein (GFAP) were determined by Single Molecule Assay (SIMOA

Indexed as

Alzheimer DiseaseBiomarkersAgedAged, 80 and overCognitive DysfunctionEarly DiagnosisFemaleFrontotemporal DementiaGlial Fibrillary Acidic ProteinHumansLewy Body DiseaseMaleMiddle AgedNeurofilament ProteinsROC Curvetau ProteinsBiomarkersGFAP protein, humanGlial Fibrillary Acidic Proteinneurofilament protein LNeurofilament Proteinstau ProteinsAlzheimer’s diseasebiomarkerdiagnosisfrontotemporal dementiaplasmaSIMOA

Identifiers

PMID37762457
PMCPMC10532221
OpenAlexW4386815082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.