Evidence map›Paper›PMID 37762412›Full record

ArticleInternational journal of molecular sciences2023

Cooking, Digestion, and In Vitro Colonic Fermentation of Nigerian Wholegrains Affect Phenolic Acid Metabolism and Gut Microbiota Composition.

Oghenerukevwe Anne Obayiuwana, Volker Behrends, Yolanda Calle-Patino, Monica Barone, Silvia Turroni, Patrizia Brigidi, Adele Costabile, Giulia Corona

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Oghenerukevwe Anne ObayiuwanaSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.
Volker BehrendsSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.ORCID 0000-0003-4855-5497
Yolanda Calle-PatinoSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.ORCID 0000-0002-1467-5178
Monica BaroneMicrobiomics Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-5229-570X
Silvia TurroniUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-2345-9482
Patrizia BrigidiMicrobiomics Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.
Adele CostabileSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.ORCID 0000-0003-3185-030X
Giulia CoronaSchool of Life and Health Sciences, University of Roehampton, London SW15 4JD, UK.ORCID 0000-0002-4323-5198
University of Roehampton · GBUniversity of Bologna · ITUniversity of Benin · NG

Funding

Schlumberger Foundation (Faculty for the future) and University of Roehampton n/a
6 · The paper itself

Abstract

Wholegrains contain both fibre and phenolic acids (PAs), and their gastrointestinal modifications are critical for their bioavailability and bioactivity. We evaluated the modifications on the PA profile and gut microbiota composition of selected Nigerian wholegrains, following cooking and gastrointestinal digestion. Red fonio, red millet, red sorghum, and white corn were cooked, digested, and fermented using an in vitro colonic model. A total of 26 PA derivatives were quantified in soluble and bound fractions using Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) analysis. DNA samples were analysed using 16S rRNA amplicon sequencing to profile the microbiota composition. The results show that cooking and digestion significantly affected the levels of PAs in all grains (

Indexed as

Gastrointestinal MicrobiomeChromatography, LiquidCookingDigestionEdible GrainFermentationHumansHydroxybenzoatesRNA, Ribosomal, 16STandem Mass SpectrometryHydroxybenzoatesphenolic acidRNA, Ribosomal, 16Sbioaccessibilitycookingdigestionfermentationgut microbiotanext-generation sequencingpolyphenolsUPLC-MS/MSwholegrains

Identifiers

PMID37762412
PMCPMC10531640
OpenAlexW4386784663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.