Evidence map›Paper›PMID 37762399›Full record

ArticleInternational journal of molecular sciences2023

Lenalidomide Promotes Thrombosis Formation, but Does Not Affect Platelet Activation in Multiple Myeloma.

Panpan Li, Bei Xu, Jiadai Xu, Yanyan Xu, Yawen Wang, Chen Chen, Peng Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Anticoagulants in hematologic malignancies: what is the data?Hematology. American Society of Hematology. Education Program · 2025
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Panpan LiDepartment of Hematology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.ORCID 0000-0002-1341-6115
Bei XuDepartment of Hematology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Jiadai XuDepartment of Hematology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yanyan XuKey Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200032, China.
Yawen WangDepartment of Hematology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Chen ChenDepartment of Hematology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Peng LiuDepartment of Hematology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Sun Yat-sen University · CNShanghai Jiao Tong University · CN

Funding

Jiadai Xu 82100215Jiadai Xu Grant 2023J05291Peng Liu Grant 22ZR1411400
6 · The paper itself

Abstract

Lenalidomide, a well-established drug for the treatment of multiple myeloma, significantly enhances patients' survival. Previous clinical studies have demonstrated that its main side effect is an increased risk of thrombotic events. However, the underlying mechanism remains unexplored. Therefore, this study aims to elucidate the mechanism and offer insights into the selection of clinical thrombotic prophylaxis drugs. Firstly, we conducted a retrospective analysis of clinical data from 169 newly diagnosed multiple myeloma patients who received lenalidomide. To confirm the impact of lenalidomide on thrombosis formation, FeCl

Indexed as

LenalidomideMultiple MyelomaPlatelet ActivationThrombosisAgedAnimalsBlood CoagulationBlood PlateletsDisease Models, AnimalFemaleHumansMaleMiceMiddle AgedRetrospective StudiesVenous ThrombosisLenalidomideimmunomodulatory drugsmultiple myelomaplateletthrombosis

Identifiers

PMID37762399
PMCPMC10532040
OpenAlexW4386785154

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.