Evidence map›Paper›PMID 37762377›Full record

ArticleInternational journal of molecular sciences2023

Ozonated Oil in Liposome Eyedrops Reduces the Formation of Biofilm, Selection of Antibiotic-Resistant Bacteria, and Adhesion of Bacteria to Human Corneal Cells.

Valentina Gentili, Giovanni Strazzabosco, Niccolò Salgari, Alessandra Mancini, Sabrina Rizzo, Silvia Beltrami, Giovanna Schiuma, Fabio Casciano, Andrea Alogna, Daniela Passarella and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Valentina GentiliDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-4572-5497
Giovanni StrazzaboscoDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-7227-7939
Niccolò SalgariDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Alessandra ManciniDepartment of Ophthalmology, University of "Magna Graecia", 88100 Catanzaro, Italy.
Sabrina RizzoDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.
Silvia BeltramiDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-5923-9265
Giovanna SchiumaDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-4652-5550
Fabio CascianoDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-6431-3335
Andrea AlognaDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.
Daniela PassarellaDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-6145-2874
Sergio DavinelliDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-2578-7199
Giovanni ScapagniniDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0003-1592-5586
Alessandro MedoroDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, 86100 Campobasso, Italy.ORCID 0000-0002-6285-607X
Roberta RizzoDepartment of Chemical, Pharmaceutical and Agricultural Science, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9507-9126
University of Ferrara · ITUniversity of Molise · ITMagna Graecia University · IT

Funding

University of Ferrara FAR 2021
6 · The paper itself

Abstract

The recent attention to the risk of potential permanent eye damage triggered by ocular infections has been leading to a deeper investigation of the current antimicrobials. An antimicrobial agent used in ophthalmology should possess the following characteristics: a broad antimicrobial spectrum, prompt action even in the presence of organic matter, and nontoxicity. The objective of this study is to compare the antimicrobial efficacy of widely used ophthalmic antiseptics containing povidone-iodine, chlorhexidine, and liposomes containing ozonated sunflower oil. We determined the minimum inhibitory concentration (MIC) on various microbial strains:

Indexed as

Bacterial AdhesionBiofilmsCorneaDrug Resistance, BacterialLiposomesOphthalmic SolutionsOzoneAnti-Bacterial AgentsEscherichia coliHumansMicrobial Sensitivity TestsPseudomonas aeruginosaStaphylococcus epidermidisSunflower OilAnti-Bacterial AgentsLiposomesOphthalmic SolutionsOzoneSunflower Oilantimicrobial agentsantisepticbiofilmchlorhexidineliposomal ozonated oilmultidrug-resistant organismsophthalmologypovidone-iodinetoxicity

Identifiers

PMID37762377
PMCPMC10531138
OpenAlexW4386755034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.