Evidence map›Paper›PMID 37762324›Full record

ArticleInternational journal of molecular sciences2023

miR-383-5p Regulates Preadipocyte Proliferation and Differentiation by Targeting

Meigui Wang, Jiahao Shao, Xiaoxiao Zhang, Zheliang Liu, Tao Tang, Guanhe Chen, Siqi Xia, Kaisen Zhao, Zhe Kang, Wenqiang Sun and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pulling the trigger: Noncoding RNAs in white adipose tissue browning.Reviews in endocrine & metabolic disorders · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Meigui WangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Jiahao ShaoCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Xiaoxiao ZhangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Zheliang LiuCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Tao TangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Guanhe ChenCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Siqi XiaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Kaisen ZhaoCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Zhe KangCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Wenqiang SunFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.
Xianbo JiaFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-6885-4104
Jie WangFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-1399-7079
Songjia LaiFarm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu 611130, China.
Sichuan Agricultural University · CN

Funding

high quality and characteristic rabbit breeding materials and methods innovation and new varie-ty breeding. (2021YFYZ0033)
6 · The paper itself

Abstract

Obesity has become a major health problem worldwide, and increasing evidence supports the importance of microRNAs (miRNAs) in its pathogenesis. Recently, we found that miR-383-5p_1 is highly expressed in the perirenal fat of high-fat-fed rabbits, but it is not yet known whether miR-383-5p is involved in lipid metabolism. Here, we used transcriptome sequencing technology to screen 1642 known differentially expressed genes between miR-383-5p mimic groups and miR-383-5p negative control groups. Gene Ontology Resource (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were enriched in the pathway related to lipid metabolism, and glycine biosynthesis, the NOD receptor signal pathway and nonalcoholic fatty liver were significantly enriched. Afterwards, our research results indicated that miR-383-5p can promote the proliferation and differentiation of rabbit preadipocytes, and there is a direct targeting relationship with

Indexed as

LagomorphaMicroRNAsAnimalsCell ProliferationLipid MetabolismLipidsObesityRabbitsLipidsMicroRNAsdifferentiationmiR-383-5ppreadipocytesproliferationrabbitsRAD51AP1

Identifiers

PMID37762324
PMCPMC10531573
OpenAlexW4386723235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.