Evidence map›Paper›PMID 37762308›Full record

ArticleInternational journal of molecular sciences2023

Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to

Fabian Schnitker, Yongjie Liu, Simone Keitsch, Matthias Soddemann, Hedda Luise Verhasselt, Jan Kehrmann, Heike Grassmé, Markus Kamler, Erich Gulbins, Yuqing Wu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Insights on the Pathogenesis ofJournal of clinical medicine · 2025
    Review
  3. Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections.Journal of molecular medicine (Berlin, Germany) · 2025
    Article
  4. Protein interactions, calcium, phosphorylation, and cholesterol modulate CFTR cluster formation on membranes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. TheMicrobiology (Reading, England) · 2025
    Article
  6. ThebioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Fabian SchnitkerDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Yongjie LiuDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0001-7259-9495
Simone KeitschDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Matthias SoddemannDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Hedda Luise VerhasseltInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0002-5601-2444
Jan KehrmannInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0002-1494-9191
Heike GrassméDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Markus KamlerWest German Heart and Vascular Center, Thoracic Transplantation, Department of Thoracic and Cardiovascular Surgery, University Hospital Essen, University Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0001-6608-8496
Erich GulbinsDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.
Yuqing WuDepartment of Molecular Biology, Institute of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, 45122 Essen, Germany.ORCID 0000-0001-8752-0401
Institute of Molecular Biology · DEUniversity of Duisburg-Essen · DEWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is an autosomal recessive disorder caused by the deficiency of the cystic fibrosis transmembrane conductance regulator (CFTR) and often leads to pulmonary infections caused by various pathogens, including

Indexed as

Cystic FibrosisMycobacterium Infections, NontuberculousAnimalsCystic Fibrosis Transmembrane Conductance RegulatorHumansMiceNontuberculous MycobacteriaSphingosineCystic Fibrosis Transmembrane Conductance RegulatorSphingosinecystic fibrosisMycobacterium abscessussphingolipidssphingosine

Identifiers

PMID37762308
PMCPMC10530875
OpenAlexW4386645229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.