Evidence map›Paper›PMID 37762235›Full record

ArticleInternational journal of molecular sciences2023

A Novel Probiotic-Based Oral Vaccine against SARS-CoV-2 Omicron Variant B.1.1.529.

Eddie Chung Ting Chau, Tsz Ching Kwong, Chun Keung Pang, Lee Tung Chan, Andrew Man Lok Chan, Xiaoqiang Yao, John Siu Lun Tam, Shun Wan Chan, George Pak Heng Leung, William Chi Shing Tai and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. COVID-19 Pandemic: Therapeutic Strategies and Vaccines.International journal of molecular sciences · 2023
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Eddie Chung Ting ChauSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Tsz Ching KwongSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-9515-092X
Chun Keung PangSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Lee Tung ChanSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Andrew Man Lok ChanSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Xiaoqiang YaoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.ORCID 0000-0002-0687-8186
John Siu Lun TamDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.
Shun Wan ChanDepartment of Food and Health Sciences, Faculty of Science and Technology, Technological and Higher Education Institute of Hong Kong, Hong Kong, China.
George Pak Heng LeungDepartment of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China.ORCID 0000-0003-3529-9367
William Chi Shing TaiDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China.ORCID 0000-0002-0771-7894
Yiu Wa KwanSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Chinese University of Hong Kong · HKHong Kong Polytechnic University · HKTechnological and Higher Education Institute of Hong Kong · HKUniversity of Hong Kong · HK

Funding

The Health Bureau of the Government of the Hong Kong Special Administrative Region of the People's Republic of China COVID190219
6 · The paper itself

Abstract

COVID-19 pandemic, caused by the SARS-CoV-2 virus, is still affecting the entire world via the rapid emergence of new contagious variants. Vaccination remains the most effective prevention strategy for viral infection, yet not all countries have sufficient access to vaccines due to limitations in manufacturing and transportation. Thus, there is an urgent need to develop an easy-to-use, safe, and low-cost vaccination approach. Genetically modified microorganisms, especially probiotics, are now commonly recognized as attractive vehicles for delivering bioactive molecules via oral and mucosal routes. In this study,

Indexed as

COVID-19VaccinesAnimalsCOVID-19 VaccinesCricetinaeHumansMesocricetusPandemicsSARS-CoV-2COVID-19 VaccinesVaccinesCOVID-19infectious diseaseLactobacillus caseiOmicronoral vaccine

Identifiers

PMID37762235
PMCPMC10530581
OpenAlexW4386601993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.