Evidence map›Paper›PMID 37762233›Full record

ArticleInternational journal of molecular sciences2023

Microfluidic Isolation of Disseminated Tumor Cells from the Bone Marrow of Breast Cancer Patients.

Léa L Volmer, Cansu E Önder, Barbara Volz, Anjali R Singh, Sara Y Brucker, Tobias Engler, Andreas D Hartkopf, André Koch

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Feasibility ofGeburtshilfe und Frauenheilkunde · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Léa L VolmerResearch Institute for Women's Health, University of Tübingen, 72076 Tübingen, Germany.
Cansu E ÖnderResearch Institute for Women's Health, University of Tübingen, 72076 Tübingen, Germany.
Barbara VolzResearch Institute for Women's Health, University of Tübingen, 72076 Tübingen, Germany.
Anjali R SinghResearch Institute for Women's Health, University of Tübingen, 72076 Tübingen, Germany.
Sara Y BruckerDepartment of Women's Health, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-5162-1542
Tobias EnglerDepartment of Women's Health, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-8063-2053
Andreas D HartkopfResearch Institute for Women's Health, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-1227-1118
André KochResearch Institute for Women's Health, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-3502-382X
University of Tübingen · DE

Funding

Deutsche Forschungsgemeinschaft Graduate School 2543/1German Cancer Aid 70112504Universitätsklinikum Tübingen 2614-0-0
6 · The paper itself

Abstract

Disseminated tumor cells (DTCs) in the bone marrow (BM) of breast cancer (BC) patients are putative precursors of metastatic disease, and their presence is associated with an adverse clinical outcome. To achieve the personalization of therapy on a clinical routine level, the characterization of DTCs and in vitro drug testing on DTCs are of great interest. Therefore, biobanking methods, as well as novel approaches to DTC isolation, need to be developed. In this study, we established a protocol for the biobanking of BM samples and evaluated a microfluidic-based separation system (Parsortix

Indexed as

Bone MarrowBreast NeoplasmsCell SeparationMicrofluidicsNeoplastic Cells, CirculatingCryopreservationFemaleHumansbreast cancerdisseminated tumor cells (DTCs)liquid biopsymicrofluidic cell separationParsortix

Identifiers

PMID37762233
PMCPMC10531360
OpenAlexW4386607675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.