Evidence map›Paper›PMID 37762225›Full record

ArticleInternational journal of molecular sciences2023

Endothelial Dysfunction in Primary Sjögren's Syndrome: Correlation with Serum Biomarkers of Disease Activity.

Alexandru Caraba, Stela Iurciuc, Mihaela Nicolin, Mircea Iurciuc

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Primary Sjogren syndrome with suspected central nervous system inflammatory involvement.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Review
  4. Sjogren's Disease and Elevated Cardiovascular Risk: Mechanisms and Treatment.Journal of cardiovascular development and disease · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Alexandru Caraba3rd Internal Medicine, Diabetes and Rheumatology Department, University of Medicine and Pharmacy "Victor Babeș", 300041 Timișoara, Romania.ORCID 0000-0003-1306-425X
Stela IurciucCardiology Department, University of Medicine and Pharmacy "Victor Babeș", 300041 Timișoara, Romania.
Mihaela NicolinCardiology Department, "Victor Popescu" Military Hospital, 300080 Timișoara, Romania.
Mircea IurciucCardiology Department, University of Medicine and Pharmacy "Victor Babeș", 300041 Timișoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROSpitalul Clinic Dr. Victor Babes · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the relationship between endothelial dysfunction and serum cytokines, anti-SSA and anti-SSB antibodies, beta-2 microglobulin levels, focus score and EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) in primary Sjögren's syndrome (pSS) patients. The study included 90 patients with pSS and 45 healthy subjects, matched for age and gender, as controls. Serum beta-2 microglobulin, total cholesterol, HDL-cholesterol, triglycerides, TNF-α, and IL-6 were analyzed in both the groups. Patients with pSS were also tested for antinuclear antibodies, anti-SAA (anti-Sjögren's syndrome-related antigen A) antibodies, anti-SSB (anti-Sjögren syndrome related antigen B) antibodies, and focus score (the histopathologic one, based on minor salivary gland biopsy). Endothelial dysfunction was assessed by means of flow-mediated dilation (FMD) in the brachial artery. Data are presented as mean ± standard deviation. Statistical analysis was performed using the

Indexed as

Sjogren's SyndromeVascular DiseasesAntibodies, AntinuclearBiomarkersCytokinesHumansInterleukin-6Tumor Necrosis Factor-alphaAntibodies, AntinuclearBiomarkersCytokinesInterleukin-6Tumor Necrosis Factor-alphabeta-2 microglobulincytokinesendothelial dysfunctionSjögren’s syndrome

Identifiers

PMID37762225
PMCPMC10531316
OpenAlexW4386601963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.