Evidence map›Paper›PMID 37762176›Full record

ArticleInternational journal of molecular sciences2023

Milk-Derived Small Extracellular Vesicles Promote Osteogenic Differentiation and Inhibit Inflammation via microRNA-21.

Runyuan Liu, Shuo Liu, Saixuan Wu, Meng Xia, Wanqing Liu, Lina Wang, Ming Dong, Weidong Niu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Therapeutic Potential of Bovine Milk-Derived Extracellular Vesicles.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Runyuan LiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Shuo LiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Saixuan WuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.ORCID 0000-0001-5717-4296
Meng XiaSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Wanqing LiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Lina WangSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Ming DongSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Weidong NiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Dalian Medical University · CN

Funding

Dalian Science and Technology Innovation Fund 2022JJ13SN063Liaoning Province Doctor Startup Foundation 2022-BS-237National Natural Science Foundation of China 82100998National Natural Science Foundation of China 82270971Provincial Basic Scientific Research Project of Liaoning Education Department LJKZ0841Science and Technology Plan of Liaoning Province 2021JH2/10300027
6 · The paper itself

Abstract

Chronic apical periodontitis (CAP) is a disease with characteristics of inflammation and bone loss. In this study, our objective was to examine the function of small extracellular vesicles (sEVs) obtained from milk in encouraging osteogenic differentiation and inhibiting inflammation by

Indexed as

Extracellular VesiclesMicroRNAsAnimalsCell DifferentiationInflammationMiceMilkOsteogenesisMicroRNAsMIRN21 microRNA, mousechronic apical periodontitismilkmiR-21small extracellular vesicles

Identifiers

PMID37762176
PMCPMC10531249
OpenAlexW4386602533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.