Evidence map›Paper›PMID 37762163›Full record

ArticleInternational journal of molecular sciences2023

Human Prune Regulates the Metabolism of Mammalian Inorganic Polyphosphate and Bioenergetics.

Ernest R Scoma, Renata T Da Costa, Ho Hang Leung, Pedro Urquiza, Mariona Guitart-Mampel, Vedangi Hambardikar, Lindsey M Riggs, Ching-On Wong, Maria E Solesio

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Inorganic Polyphosphate and Human Diseases.Progress in molecular and subcellular biology · 2026
    Review
  4. Review
  5. Polyphosphate: a cellular Swiss army knife.Current opinion in biotechnology · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ernest R ScomaDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.
Renata T Da CostaDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.
Ho Hang LeungDepartment of Biological Sciences, Rutgers University, Newark, NJ 07102, USA.
Pedro UrquizaDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.ORCID 0000-0002-3074-9077
Mariona Guitart-MampelDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.ORCID 0000-0002-9768-4706
Vedangi HambardikarDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.
Lindsey M RiggsDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.
Ching-On WongDepartment of Biological Sciences, Rutgers University, Newark, NJ 07102, USA.ORCID 0000-0002-8602-2125
Maria E SolesioDepartment of Biology, and Center for Computational and Integrative Biology, Rutgers University, Camden, NJ 08103, USA.ORCID 0000-0002-8105-1701
Rutgers, The State University of New Jersey · US

Funding

Role of TTYH1 in mobilizing lipids and ApoE in glia: Implications for brain aging and neurodegenerationR01AG081379 · NIA · RUTGERS THE STATE UNIV OF NJ NEWARK · PI Ching-On Wong · 2023 to 2026
$1.4M
Inorganic polyphosphate as a chaperone in aging and in neurodegenerative diseasesR00AG055701 · NIA · RUTGERS THE STATE UNIV OF NJ CAMDEN · PI SOLESIO TORREGROSA, MARIA DE LA ENCARNACION · 2019 to 2021
$733k
NIA NIH HHS R00 AG055701NIA NIH HHS R01 AG081379NIH HHS 5R00AG055701NIH HHS R01AG081379
6 · The paper itself

Abstract

Inorganic polyphosphate (polyP) is an evolutionarily conserved and ubiquitous polymer that is present in all studied organisms. PolyP consists of orthophosphates (Pi) linked together by phosphoanhydride bonds. The metabolism of polyP still remains poorly understood in higher eukaryotes. Currently, only F

Indexed as

Acid Anhydride HydrolasesEnergy MetabolismPolyphosphatesAnimalsHEK293 CellsHumansMitochondriaAcid Anhydride HydrolasesexopolyphosphatasePolyphosphatesh-Pruneinorganic polyphosphate (polyP)mammalian bioenergeticspolyP’s metabolism

Identifiers

PMID37762163
PMCPMC10531210
OpenAlexW4386547013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.