Evidence map›Paper›PMID 37762123›Full record

ArticleInternational journal of molecular sciences2023

Guanylation Reactions for the Rational Design of Cancer Therapeutic Agents.

Almudena Del Campo-Balguerías, Blanca Parra-Cadenas, Cristina Nieto-Jimenez, Iván Bravo, Consuelo Ripoll, Elisa Poyatos-Racionero, Pawel Gancarski, Fernando Carrillo-Hermosilla, Carlos Alonso-Moreno, Alberto Ocaña

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Almudena Del Campo-BalgueríasUnidad nanoDrug, Centro Regional de Investigaciones Biomédicas, Universidad de Castilla-La Mancha, 02008 Albacete, Spain.ORCID 0000-0002-0119-6733
Blanca Parra-CadenasDepartamento de Química Inorgánica, Orgánica y Bioquímica-Centro de Innovación en Química Avanzada (ORFEO-CINQA), Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0002-2528-3778
Cristina Nieto-JimenezExperimental Therapeutics Unit, Hospital Clínico San Carlos, IdISSC, Fundación Jiménez Díaz, START, 28040 Madrid, Spain.
Iván BravoUnidad nanoDrug, Centro Regional de Investigaciones Biomédicas, Universidad de Castilla-La Mancha, 02008 Albacete, Spain.ORCID 0000-0003-1589-5399
Consuelo RipollUnidad nanoDrug, Centro Regional de Investigaciones Biomédicas, Universidad de Castilla-La Mancha, 02008 Albacete, Spain.
Elisa Poyatos-RacioneroCancerappy, Avda Ribera De Axpe, 28, 48950 Erandio, Spain.ORCID 0000-0001-8294-5945
Pawel GancarskiCancerappy, Avda Ribera De Axpe, 28, 48950 Erandio, Spain.
Fernando Carrillo-HermosillaDepartamento de Química Inorgánica, Orgánica y Bioquímica-Centro de Innovación en Química Avanzada (ORFEO-CINQA), Universidad de Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0002-1187-7719
Carlos Alonso-MorenoUnidad nanoDrug, Centro Regional de Investigaciones Biomédicas, Universidad de Castilla-La Mancha, 02008 Albacete, Spain.ORCID 0000-0002-7588-0781
Alberto OcañaExperimental Therapeutics Unit, Hospital Clínico San Carlos, IdISSC, Fundación Jiménez Díaz, START, 28040 Madrid, Spain.ORCID 0000-0002-1067-9630
University of Castilla-La Mancha · ESHospital Clínico San Carlos · ES

Funding

Instituto de Salud Carlos III PI16/01121Instituto de Salud Carlos III PI19/00808Junta de Comunidades de Castilla-La Mancha SBPLY/21/180501/000050Ministerio de ciencia e Innovación y Agencia Estatal de la Investigación CPP2021-008597Ministerio de Ciencia e Innovación y Agencia Estatal de la Investigación PID2020-117353GB-I00Ministerio de Ciencia e Innovación y Agencia Estatal de la Investigación PID2020-117788RB-I00Ministerio de Ciencia e Innovación y Agencia Estatal de la Investigación RED2022-134287-T
6 · The paper itself

Abstract

The modular synthesis of the guanidine core by guanylation reactions using commercially available ZnEt

Indexed as

GuanidinesNeoplasmsApoptosisCell DeathGuanidineHumansGuanidineGuanidinesbreast cancerguanidinesguanylation reactionshigh-throughput testing

Identifiers

PMID37762123
PMCPMC10530677
OpenAlexW4386496625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.