Evidence map›Paper›PMID 37762057›Full record

ArticleInternational journal of molecular sciences2023

Method Development for Determination of Doripenem in Human Plasma via Capillary Electrophoresis Coupled with Field-Enhanced Sample Stacking and Sweeping.

Hsin-Hua Liang, Yu-Chao Lin, Chin-Chuan Hung, Yu-Chi Hou, Yi-Hui Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hsin-Hua LiangSchool of Pharmacy, China Medical University, Taichung 406040, Taiwan.
Yu-Chao LinDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, China Medical University Hospital, Taichung 404332, Taiwan.
Chin-Chuan HungSchool of Pharmacy, China Medical University, Taichung 406040, Taiwan.ORCID 0000-0003-1395-4834
Yu-Chi HouSchool of Pharmacy, China Medical University, Taichung 406040, Taiwan.ORCID 0000-0002-3995-7219
Yi-Hui LinSchool of Pharmacy, China Medical University, Taichung 406040, Taiwan.ORCID 0000-0002-4971-3488
China Medical University · TW

Funding

China Medical University CMU111-MF-46National Science and Technology Council of Taiwan MOST 106-2113-M-039-004 -National Science and Technology Council of Taiwan NSTC 112-2113-M-039-005 -
6 · The paper itself

Abstract

In this study, we established a novel capillary electrophoresis method for monitoring the concentration of doripenem in human plasma. As a time-dependent antibiotic, doripenem maximizes its antibacterial effects and minimizes the potential for antibiotic resistance through careful therapeutic drug monitoring. Two online preconcentration techniques, field-enhanced sample stacking (FESS) and sweeping, were coupled to enhance the detection sensitivity. Briefly, an uncoated fused silica capillary (40 cm × 50 μm i.d) was rinsed with a high conductivity buffer (HCB) composed of 150 mM phosphate buffer (NaH

Indexed as

DoripenemElectrophoresis, CapillaryAnti-Bacterial AgentsCarbapenemsHumansLimit of DetectionReproducibility of ResultsSolid Phase ExtractionAnti-Bacterial AgentsCarbapenemsDoripenemcarbapenemsdoripenemFESS-sweeping MEKChuman plasmaonline preconcentration

Identifiers

PMID37762057
PMCPMC10531396
OpenAlexW4386483738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.