Evidence map›Paper›PMID 37762050›Full record

ArticleInternational journal of molecular sciences2023

Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine: A Prospective Study of Phase 3 Clinical Trial Participants.

Mohammad Arastoo, Michael P Mazanetz, Sonya Miller, Helen Shiells, Claire Hull, Keith Robinson, John M D Storey, Charles R Harrington, Claude M Wischik

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Mohammad ArastooSchool of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZP, UK.
Michael P MazanetzNovaData Solutions Ltd., 15 Monreith Rd, Newlands, Glasgow G43 2NX, UK.
Sonya MillerTauRx Therapeutics Ltd., 395 King Street, Aberdeen AB24 3FX, UK.
Helen ShiellsTauRx Therapeutics Ltd., 395 King Street, Aberdeen AB24 3FX, UK.
Claire HullTauRx Therapeutics Ltd., 395 King Street, Aberdeen AB24 3FX, UK.ORCID 0000-0001-6215-6279
Keith RobinsonSyneos Health, LLC, Morrisville, NC 27560, USA.ORCID 0000-0002-5410-5233
John M D StoreyDepartment of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.
Charles R HarringtonSchool of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZP, UK.ORCID 0000-0003-2250-3920
Claude M WischikSchool of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen AB25 2ZP, UK.
University of Aberdeen · GBTauRx (United Kingdom) · GBSyneos Health (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methylthioninium chloride (MTC) is a standard treatment for methaemoglobinaemia. A preparation of reduced MTC has been reported to increase blood oxygen saturation (SpO

Indexed as

COVID-19Methylene BlueHemeHumansHypoxiaIronMethemoglobinOxygenProspective StudiesHemehydromethylthionineIronMethemoglobinMethylene BlueOxygenanti-hypoxaemiaCOVID-19hydromethylthioninehypoxaemiaSARS-CoV-2

Identifiers

PMID37762050
PMCPMC10531415
OpenAlexW4386483847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.